deltatrials
Terminated PHASE1 INTERVENTIONAL 8-arm NCT03426995

First-time-in-Human (FTIH) Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single (in Both Fed and Fasted States) or Repeat Doses of GSK3358699

A Randomised, Double-blind (Sponsor Open), Placebo-controlled, Three Part Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single (in Both Fed and Fasted States) or Repeat Doses of GSK3358699 in Healthy Male Participants

Sponsor: GlaxoSmithKline

Updated 12 times since 2018 Last updated: Nov 6, 2020 Started: Mar 13, 2018 Primary completion: May 2, 2019 Completion: May 2, 2019
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

The trial was terminated for strategic reasons following the emergence of new data.

Listed as NCT03426995, this PHASE1 trial focuses on Arthritis, Rheumatoid and remains terminated or withdrawn. Sponsored by GlaxoSmithKline, it has been updated 12 times since 2018, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Mar 2018 – ~Apr 2018 · 31 days · monthly snapshotNot Yet Recruiting~Apr 2018 – ~Jun 2018 · 2 months · monthly snapshotRecruiting~Jun 2018 – ~Jul 2018 · 30 days · monthly snapshotRecruiting~Jul 2018 – ~Oct 2018 · 3 months · monthly snapshotRecruiting~Oct 2018 – ~Nov 2019 · 13 months · monthly snapshotRecruiting~Nov 2019 – ~Mar 2020 · 4 months · monthly snapshotSuspended~Mar 2020 – ~Jan 2021 · 10 months · monthly snapshotTerminated~Jan 2021 – ~Jan 2022 · 12 months · monthly snapshotTerminated~Jan 2022 – ~Mar 2022 · 59 days · monthly snapshotTerminated~Mar 2022 – ~Jul 2024 · 28 months · monthly snapshotTerminated~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotTerminated~Sep 2024 – present · 22 months · monthly snapshotTerminated

Change History

12 versions recorded
  1. Sep 2024 — Present [monthly]

    Terminated PHASE1

  2. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE1

  3. Mar 2022 — Jul 2024 [monthly]

    Terminated PHASE1

  4. Jan 2022 — Mar 2022 [monthly]

    Terminated PHASE1

  5. Jan 2021 — Jan 2022 [monthly]

    Terminated PHASE1

Show 7 earlier versions
  1. Mar 2020 — Jan 2021 [monthly]

    Terminated PHASE1

    Status: SuspendedTerminated

  2. Nov 2019 — Mar 2020 [monthly]

    Suspended PHASE1

    Status: RecruitingSuspended

  3. Oct 2018 — Nov 2019 [monthly]

    Recruiting PHASE1

  4. Jul 2018 — Oct 2018 [monthly]

    Recruiting PHASE1

  5. Jun 2018 — Jul 2018 [monthly]

    Recruiting PHASE1

  6. Apr 2018 — Jun 2018 [monthly]

    Recruiting PHASE1

    Status: Not Yet RecruitingRecruiting

  7. Mar 2018 — Apr 2018 [monthly]

    Not Yet Recruiting PHASE1

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • GlaxoSmithKline
Data source: GlaxoSmithKline

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations