deltatrials
Terminated PHASE1 INTERVENTIONAL 3-arm NCT03435250

Study of AG-270 in Participants With Advanced Solid Tumors or Lymphoma With MTAP Loss

A Phase 1 Study of AG-270 in the Treatment of Subjects With Advanced Solid Tumors or Lymphoma With Homozygous Deletion of MTAP

Sponsor: Institut de Recherches Internationales Servier

Conditions Advanced Solid Tumors Lymphoma
Interventions AG-270 docetaxel gemcitabine nab-paclitaxel
Updated 39 times since 2018 Last updated: Jul 24, 2024 Started: Mar 4, 2018 Primary completion: Apr 20, 2023 Completion: Apr 20, 2023
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Strategic reasons

Other terminated trials from Institut de Recherches Internationales Servier

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A PHASE1 clinical study on Advanced Solid Tumors and Lymphoma, this trial is terminated or withdrawn. The trial is conducted by Institut de Recherches Internationales Servier and has accumulated 39 data snapshots since 2018. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Mar 2018 – ~Jun 2018 · 3 months · monthly snapshot~Jun 2018 – ~Aug 2018 · 2 months · monthly snapshot~Aug 2018 – ~Feb 2019 · 6 months · monthly snapshot~Feb 2019 – ~May 2019 · 3 months · monthly snapshot~May 2019 – ~Jul 2019 · 2 months · monthly snapshot~Jul 2019 – ~Aug 2019 · 31 days · monthly snapshot~Aug 2019 – ~Oct 2019 · 2 months · monthly snapshot~Oct 2019 – ~Nov 2019 · 31 days · monthly snapshot~Nov 2019 – ~Dec 2019 · 30 days · monthly snapshot~Dec 2019 – ~Jan 2020 · 31 days · monthly snapshot~Jan 2020 – ~Feb 2020 · 31 days · monthly snapshot~Feb 2020 – ~Mar 2020 · 29 days · monthly snapshot~Mar 2020 – ~Apr 2020 · 31 days · monthly snapshot~Apr 2020 – ~May 2020 · 30 days · monthly snapshot~May 2020 – ~Jun 2020 · 31 days · monthly snapshot~Jun 2020 – ~Jul 2020 · 30 days · monthly snapshot~Jul 2020 – ~Aug 2020 · 31 days · monthly snapshot~Aug 2020 – ~Sep 2020 · 31 days · monthly snapshot~Sep 2020 – ~Dec 2020 · 3 months · monthly snapshot~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshot~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshot~Feb 2021 – ~Mar 2021 · 28 days · monthly snapshot~Mar 2021 – ~Apr 2021 · 31 days · monthly snapshot~Apr 2021 – ~May 2021 · 30 days · monthly snapshot~May 2021 – ~Jun 2021 · 31 days · monthly snapshot~Jun 2021 – ~Sep 2021 · 3 months · monthly snapshot~Sep 2021 – ~Jun 2022 · 9 months · monthly snapshot~Jun 2022 – ~Jul 2022 · 30 days · monthly snapshot~Jul 2022 – ~Sep 2022 · 2 months · monthly snapshot~Sep 2022 – ~Jun 2023 · 9 months · monthly snapshot~Jun 2023 – ~Jul 2023 · 30 days · monthly snapshot~Jul 2023 – ~Nov 2023 · 4 months · monthly snapshot~Nov 2023 – ~May 2024 · 6 months · monthly snapshot~May 2024 – ~Jun 2024 · 31 days · monthly snapshot~Jun 2024 – ~Jul 2024 · 30 days · monthly snapshot~Jul 2024 – ~Aug 2024 · 31 days · monthly snapshot~Aug 2024 – ~Sep 2024 · 31 days · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – present · 10 months · monthly snapshot

Change History

39 versions recorded

  1. Sep 2025 — Present [monthly]

    Terminated PHASE1

  2. Sep 2024 — Sep 2025 [monthly]

    Terminated PHASE1

  3. Aug 2024 — Sep 2024 [monthly]

    Terminated PHASE1

  4. Jul 2024 — Aug 2024 [monthly]

    Terminated PHASE1

  5. Jun 2024 — Jul 2024 [monthly]

    Terminated PHASE1

▶ Show 34 earlier versions

  1. May 2024 — Jun 2024 [monthly]

    Terminated PHASE1

  2. Nov 2023 — May 2024 [monthly]

    Terminated PHASE1

  3. Jul 2023 — Nov 2023 [monthly]

    Terminated PHASE1

    Status: Completed → Terminated

  4. Jun 2023 — Jul 2023 [monthly]

    Completed PHASE1

    Status: Active Not Recruiting → Completed

  5. Sep 2022 — Jun 2023 [monthly]

    Active Not Recruiting PHASE1

    Status: Recruiting → Active Not Recruiting

  6. Jul 2022 — Sep 2022 [monthly]

    Recruiting PHASE1

  7. Jun 2022 — Jul 2022 [monthly]

    Recruiting PHASE1

  8. Sep 2021 — Jun 2022 [monthly]

    Recruiting PHASE1

  9. Jun 2021 — Sep 2021 [monthly]

    Recruiting PHASE1

  10. May 2021 — Jun 2021 [monthly]

    Recruiting PHASE1

  11. Apr 2021 — May 2021 [monthly]

    Recruiting PHASE1

  12. Mar 2021 — Apr 2021 [monthly]

    Recruiting PHASE1

  13. Feb 2021 — Mar 2021 [monthly]

    Recruiting PHASE1

  14. Jan 2021 — Feb 2021 [monthly]

    Recruiting PHASE1

  15. Dec 2020 — Jan 2021 [monthly]

    Recruiting PHASE1

  16. Sep 2020 — Dec 2020 [monthly]

    Recruiting PHASE1

  17. Aug 2020 — Sep 2020 [monthly]

    Recruiting PHASE1

  18. Jul 2020 — Aug 2020 [monthly]

    Recruiting PHASE1

  19. Jun 2020 — Jul 2020 [monthly]

    Recruiting PHASE1

  20. May 2020 — Jun 2020 [monthly]

    Recruiting PHASE1

  21. Apr 2020 — May 2020 [monthly]

    Recruiting PHASE1

  22. Mar 2020 — Apr 2020 [monthly]

    Recruiting PHASE1

  23. Feb 2020 — Mar 2020 [monthly]

    Recruiting PHASE1

  24. Jan 2020 — Feb 2020 [monthly]

    Recruiting PHASE1

  25. Dec 2019 — Jan 2020 [monthly]

    Recruiting PHASE1

  26. Nov 2019 — Dec 2019 [monthly]

    Recruiting PHASE1

  27. Oct 2019 — Nov 2019 [monthly]

    Recruiting PHASE1

  28. Aug 2019 — Oct 2019 [monthly]

    Recruiting PHASE1

  29. Jul 2019 — Aug 2019 [monthly]

    Recruiting PHASE1

  30. May 2019 — Jul 2019 [monthly]

    Recruiting PHASE1

  31. Feb 2019 — May 2019 [monthly]

    Recruiting PHASE1

  32. Aug 2018 — Feb 2019 [monthly]

    Recruiting PHASE1

  33. Jun 2018 — Aug 2018 [monthly]

    Recruiting PHASE1

  34. Mar 2018 — Jun 2018 [monthly]

    Recruiting PHASE1

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Institut de Recherches Internationales Servier
Data source: Servier

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations