A Long Term Safety Study of BCX7353 in Hereditary Angioedema (APeX-S)
An Open-label Study to Evaluate the Long-term Safety of Daily Oral BCX7353 in Subjects With Type I and II Hereditary Angioedema
Sponsor: BioCryst Pharmaceuticals
Listed as NCT03472040, this PHASE2/PHASE3 trial focuses on HAE and Hereditary Angioedema and remains completed. Sponsored by BioCryst Pharmaceuticals, it has been updated 23 times since 2018, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.
Status Flow
Change History
23 versions recorded-
Sep 2025 — Present [monthly]
Completed PHASE2/PHASE3
-
Sep 2024 — Sep 2025 [monthly]
Completed PHASE2/PHASE3
-
Jul 2024 — Sep 2024 [monthly]
Completed PHASE2/PHASE3
Phase: PHASE2_PHASE3 → PHASE2/PHASE3
-
Jul 2023 — Jul 2024 [monthly]
Completed PHASE2_PHASE3
-
Feb 2023 — Jul 2023 [monthly]
Completed PHASE2_PHASE3
Status: Active Not Recruiting → Completed
▶ Show 18 earlier versions
-
Jan 2021 — Feb 2023 [monthly]
Active Not Recruiting PHASE2_PHASE3
Status: Recruiting → Active Not Recruiting
-
Nov 2020 — Jan 2021 [monthly]
Recruiting PHASE2_PHASE3
-
Aug 2020 — Nov 2020 [monthly]
Recruiting PHASE2_PHASE3
-
May 2020 — Aug 2020 [monthly]
Recruiting PHASE2_PHASE3
-
Apr 2020 — May 2020 [monthly]
Recruiting PHASE2_PHASE3
-
Jan 2020 — Apr 2020 [monthly]
Recruiting PHASE2_PHASE3
-
Dec 2019 — Jan 2020 [monthly]
Recruiting PHASE2_PHASE3
-
Oct 2019 — Dec 2019 [monthly]
Recruiting PHASE2_PHASE3
-
Aug 2019 — Oct 2019 [monthly]
Recruiting PHASE2_PHASE3
-
Apr 2019 — Aug 2019 [monthly]
Recruiting PHASE2_PHASE3
-
Dec 2018 — Apr 2019 [monthly]
Recruiting PHASE2_PHASE3
-
Nov 2018 — Dec 2018 [monthly]
Recruiting PHASE2_PHASE3
-
Oct 2018 — Nov 2018 [monthly]
Recruiting PHASE2_PHASE3
-
Sep 2018 — Oct 2018 [monthly]
Recruiting PHASE2_PHASE3
-
Aug 2018 — Sep 2018 [monthly]
Recruiting PHASE2_PHASE3
-
Jul 2018 — Aug 2018 [monthly]
Recruiting PHASE2_PHASE3
-
Jun 2018 — Jul 2018 [monthly]
Recruiting PHASE2_PHASE3
-
Apr 2018 — Jun 2018 [monthly]
Recruiting PHASE2_PHASE3
First recorded
Feb 2018
Trial started
Per CT.gov start date — pre-dates our first snapshot
Eligibility Summary
No eligibility information available.
Contact Information
- BioCryst Pharmaceuticals
For direct contact, visit the study record on ClinicalTrials.gov .