deltatrials
Completed PHASE1/PHASE2 INTERVENTIONAL 4-arm NCT03497676

More Options for Children and Adolescents (MOCHA): Oral and Long-Acting Injectable Cabotegravir and Rilpivirine in HIV-Infected Children and Adolescents (MOCHA)

Phase I/II Study of the Safety, Acceptability, Tolerability, and Pharmacokinetics of Oral and Long-Acting Injectable Cabotegravir and Long-Acting Injectable Rilpivirine in Virologically Suppressed HIV-Infected Children and Adolescents

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Conditions HIV Infections
Updated 39 times since 2018 Last updated: Jan 9, 2026 Started: Apr 3, 2019 Primary completion: Feb 18, 2023 Completion: Apr 22, 2025
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE1/PHASE2 trial investigates HIV Infections and is currently completed. National Institute of Allergy and Infectious Diseases (NIAID) leads this study, which shows 39 recorded versions since 2019 — indicating substantial longitudinal coverage. Longitudinal tracking of infectious disease trials helps identify durability of treatment effects.

Status Flow

~May 2018 – ~Aug 2018 · 3 months · monthly snapshot~Aug 2018 – ~Sep 2018 · 31 days · monthly snapshot~Sep 2018 – ~Oct 2018 · 30 days · monthly snapshot~Oct 2018 – ~Nov 2018 · 31 days · monthly snapshot~Nov 2018 – ~Jan 2019 · 2 months · monthly snapshot~Jan 2019 – ~Feb 2019 · 31 days · monthly snapshot~Feb 2019 – ~Mar 2019 · 28 days · monthly snapshot~Mar 2019 – ~Apr 2019 · 31 days · monthly snapshot~Apr 2019 – ~May 2019 · 30 days · monthly snapshot~May 2019 – ~Jun 2019 · 31 days · monthly snapshot~Jun 2019 – ~Aug 2019 · 2 months · monthly snapshot~Aug 2019 – ~Sep 2019 · 31 days · monthly snapshot~Sep 2019 – ~Oct 2019 · 30 days · monthly snapshot~Oct 2019 – ~Jan 2020 · 3 months · monthly snapshot~Jan 2020 – ~May 2020 · 4 months · monthly snapshot~May 2020 – ~Jun 2020 · 31 days · monthly snapshot~Jun 2020 – ~Sep 2020 · 3 months · monthly snapshot~Sep 2020 – ~Jan 2021 · 4 months · monthly snapshot~Jan 2021 – ~Jun 2021 · 5 months · monthly snapshot~Jun 2021 – ~Sep 2021 · 3 months · monthly snapshot~Sep 2021 – ~Dec 2021 · 3 months · monthly snapshot~Dec 2021 – ~Feb 2022 · 2 months · monthly snapshot~Feb 2022 – ~Mar 2022 · 28 days · monthly snapshot~Mar 2022 – ~May 2022 · 2 months · monthly snapshot~May 2022 – ~Jul 2022 · 2 months · monthly snapshot~Jul 2022 – ~Oct 2022 · 3 months · monthly snapshot~Oct 2022 – ~Jan 2023 · 3 months · monthly snapshot~Jan 2023 – ~Mar 2023 · 59 days · monthly snapshot~Mar 2023 – ~Apr 2023 · 31 days · monthly snapshot~Apr 2023 – ~Jul 2023 · 3 months · monthly snapshot~Jul 2023 – ~Sep 2023 · 2 months · monthly snapshot~Sep 2023 – ~Jun 2024 · 9 months · monthly snapshot~Jun 2024 – ~Jul 2024 · 30 days · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Oct 2024 · 30 days · monthly snapshot~Oct 2024 – ~Aug 2025 · 10 months · monthly snapshot~Aug 2025 – ~Oct 2025 · 2 months · monthly snapshot~Oct 2025 – ~Feb 2026 · 4 months · monthly snapshot~Feb 2026 – present · 5 months · monthly snapshot

Change History

39 versions recorded
  1. Feb 2026 — Present [monthly]

    Completed PHASE1/PHASE2

  2. Oct 2025 — Feb 2026 [monthly]

    Completed PHASE1/PHASE2

  3. Aug 2025 — Oct 2025 [monthly]

    Completed PHASE1/PHASE2

    Status: Active Not RecruitingCompleted

  4. Oct 2024 — Aug 2025 [monthly]

    Active Not Recruiting PHASE1/PHASE2

  5. Sep 2024 — Oct 2024 [monthly]

    Active Not Recruiting PHASE1/PHASE2

Show 34 earlier versions
  1. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE1/PHASE2

    Phase: PHASE1_PHASE2PHASE1/PHASE2

  2. Jun 2024 — Jul 2024 [monthly]

    Active Not Recruiting PHASE1_PHASE2

    Status: RecruitingActive Not Recruiting

  3. Sep 2023 — Jun 2024 [monthly]

    Recruiting PHASE1_PHASE2

  4. Jul 2023 — Sep 2023 [monthly]

    Recruiting PHASE1_PHASE2

  5. Apr 2023 — Jul 2023 [monthly]

    Recruiting PHASE1_PHASE2

  6. Mar 2023 — Apr 2023 [monthly]

    Recruiting PHASE1_PHASE2

  7. Jan 2023 — Mar 2023 [monthly]

    Recruiting PHASE1_PHASE2

  8. Oct 2022 — Jan 2023 [monthly]

    Recruiting PHASE1_PHASE2

  9. Jul 2022 — Oct 2022 [monthly]

    Recruiting PHASE1_PHASE2

  10. May 2022 — Jul 2022 [monthly]

    Recruiting PHASE1_PHASE2

  11. Mar 2022 — May 2022 [monthly]

    Recruiting PHASE1_PHASE2

  12. Feb 2022 — Mar 2022 [monthly]

    Recruiting PHASE1_PHASE2

  13. Dec 2021 — Feb 2022 [monthly]

    Recruiting PHASE1_PHASE2

  14. Sep 2021 — Dec 2021 [monthly]

    Recruiting PHASE1_PHASE2

    Status: Active Not RecruitingRecruiting

  15. Jun 2021 — Sep 2021 [monthly]

    Active Not Recruiting PHASE1_PHASE2

  16. Jan 2021 — Jun 2021 [monthly]

    Active Not Recruiting PHASE1_PHASE2

  17. Sep 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE1_PHASE2

  18. Jun 2020 — Sep 2020 [monthly]

    Active Not Recruiting PHASE1_PHASE2

    Status: RecruitingActive Not Recruiting

  19. May 2020 — Jun 2020 [monthly]

    Recruiting PHASE1_PHASE2

  20. Jan 2020 — May 2020 [monthly]

    Recruiting PHASE1_PHASE2

  21. Oct 2019 — Jan 2020 [monthly]

    Recruiting PHASE1_PHASE2

  22. Sep 2019 — Oct 2019 [monthly]

    Recruiting PHASE1_PHASE2

  23. Aug 2019 — Sep 2019 [monthly]

    Recruiting PHASE1_PHASE2

  24. Jun 2019 — Aug 2019 [monthly]

    Recruiting PHASE1_PHASE2

  25. May 2019 — Jun 2019 [monthly]

    Recruiting PHASE1_PHASE2

  26. Apr 2019 — May 2019 [monthly]

    Recruiting PHASE1_PHASE2

    Status: Not Yet RecruitingRecruiting

  27. Mar 2019 — Apr 2019 [monthly]

    Not Yet Recruiting PHASE1_PHASE2

  28. Feb 2019 — Mar 2019 [monthly]

    Not Yet Recruiting PHASE1_PHASE2

  29. Jan 2019 — Feb 2019 [monthly]

    Not Yet Recruiting PHASE1_PHASE2

  30. Nov 2018 — Jan 2019 [monthly]

    Not Yet Recruiting PHASE1_PHASE2

  31. Oct 2018 — Nov 2018 [monthly]

    Not Yet Recruiting PHASE1_PHASE2

  32. Sep 2018 — Oct 2018 [monthly]

    Not Yet Recruiting PHASE1_PHASE2

  33. Aug 2018 — Sep 2018 [monthly]

    Not Yet Recruiting PHASE1_PHASE2

  34. May 2018 — Aug 2018 [monthly]

    Not Yet Recruiting PHASE1_PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • National Institute of Allergy and Infectious Diseases (NIAID)
  • ViiV Healthcare
Data source: National Institute of Allergy and Infectious Diseases (NIAID)

For direct contact, visit the study record on ClinicalTrials.gov .