deltatrials
Completed PHASE2 INTERVENTIONAL 1-arm NCT03739996

Long-Acting Cabotegravir Plus VRC-HIVMAB075-00-AB (VRC07-523LS) for Viral Suppression in Adults Living With HIV-1

A Study of Long-Acting Cabotegravir Plus VRC-HIVMAB075-00-AB (VRC07-523LS) to Maintain Viral Suppression in Adults Living With HIV-1

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Conditions HIV Infections
Interventions Long-Acting Injectable Cabotegravir (CAB LA) Nucleoside Reverse Transcriptase Inhibitors (NRTIs) Oral Cabotegravir (CAB) Standard of Care (SOC) ART VRC07-523LS
Updated 34 times since 2018 Last updated: May 7, 2025 Started: Dec 31, 2019 Primary completion: Apr 29, 2024 Completion: Apr 29, 2024
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE2 clinical study on HIV Infections, this trial is completed. The trial is conducted by National Institute of Allergy and Infectious Diseases (NIAID) and has accumulated 34 data snapshots since 2019. Infectious disease trials contribute critical data for public health response and treatment development.

Status Flow

~Dec 2018 – ~Jan 2019 · 31 days · monthly snapshot~Jan 2019 – ~Feb 2019 · 31 days · monthly snapshot~Feb 2019 – ~Mar 2019 · 28 days · monthly snapshot~Mar 2019 – ~Apr 2019 · 31 days · monthly snapshot~Apr 2019 – ~Jun 2019 · 2 months · monthly snapshot~Jun 2019 – ~Jul 2019 · 30 days · monthly snapshot~Jul 2019 – ~Aug 2019 · 31 days · monthly snapshot~Aug 2019 – ~Dec 2019 · 4 months · monthly snapshot~Dec 2019 – ~Feb 2020 · 2 months · monthly snapshot~Feb 2020 – ~Apr 2020 · 2 months · monthly snapshot~Apr 2020 – ~Jun 2020 · 2 months · monthly snapshot~Jun 2020 – ~Jul 2020 · 30 days · monthly snapshot~Jul 2020 – ~Oct 2020 · 3 months · monthly snapshot~Oct 2020 – ~Nov 2020 · 31 days · monthly snapshot~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshot~Jan 2021 – ~Mar 2021 · 59 days · monthly snapshot~Mar 2021 – ~May 2021 · 2 months · monthly snapshot~May 2021 – ~Sep 2021 · 4 months · monthly snapshot~Sep 2021 – ~Dec 2021 · 3 months · monthly snapshot~Dec 2021 – ~Jan 2022 · 31 days · monthly snapshot~Jan 2022 – ~Feb 2022 · 31 days · monthly snapshot~Feb 2022 – ~Jun 2022 · 4 months · monthly snapshot~Jun 2022 – ~Nov 2022 · 5 months · monthly snapshot~Nov 2022 – ~Dec 2022 · 30 days · monthly snapshot~Dec 2022 – ~Apr 2023 · 4 months · monthly snapshot~Apr 2023 – ~Jun 2023 · 2 months · monthly snapshot~Jun 2023 – ~Jul 2023 · 30 days · monthly snapshot~Jul 2023 – ~Jun 2024 · 11 months · monthly snapshot~Jun 2024 – ~Jul 2024 · 30 days · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Dec 2024 · 3 months · monthly snapshot~Dec 2024 – ~Jun 2025 · 6 months · monthly snapshot~Jun 2025 – ~Sep 2025 · 3 months · monthly snapshot~Sep 2025 – present · 11 months · monthly snapshot

Change History

34 versions recorded

  1. Sep 2025 — Present [monthly]

    Completed PHASE2

  2. Jun 2025 — Sep 2025 [monthly]

    Completed PHASE2

  3. Dec 2024 — Jun 2025 [monthly]

    Completed PHASE2

  4. Sep 2024 — Dec 2024 [monthly]

    Completed PHASE2

  5. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE2

▶ Show 29 earlier versions

  1. Jun 2024 — Jul 2024 [monthly]

    Completed PHASE2

    Status: Active Not Recruiting → Completed

  2. Jul 2023 — Jun 2024 [monthly]

    Active Not Recruiting PHASE2

  3. Jun 2023 — Jul 2023 [monthly]

    Active Not Recruiting PHASE2

  4. Apr 2023 — Jun 2023 [monthly]

    Active Not Recruiting PHASE2

  5. Dec 2022 — Apr 2023 [monthly]

    Active Not Recruiting PHASE2

  6. Nov 2022 — Dec 2022 [monthly]

    Active Not Recruiting PHASE2

    Status: Recruiting → Active Not Recruiting

  7. Jun 2022 — Nov 2022 [monthly]

    Recruiting PHASE2

  8. Feb 2022 — Jun 2022 [monthly]

    Recruiting PHASE2

  9. Jan 2022 — Feb 2022 [monthly]

    Recruiting PHASE2

  10. Dec 2021 — Jan 2022 [monthly]

    Recruiting PHASE2

  11. Sep 2021 — Dec 2021 [monthly]

    Recruiting PHASE2

  12. May 2021 — Sep 2021 [monthly]

    Recruiting PHASE2

  13. Mar 2021 — May 2021 [monthly]

    Recruiting PHASE2

  14. Jan 2021 — Mar 2021 [monthly]

    Recruiting PHASE2

  15. Nov 2020 — Jan 2021 [monthly]

    Recruiting PHASE2

  16. Oct 2020 — Nov 2020 [monthly]

    Recruiting PHASE2

  17. Jul 2020 — Oct 2020 [monthly]

    Recruiting PHASE2

  18. Jun 2020 — Jul 2020 [monthly]

    Recruiting PHASE2

  19. Apr 2020 — Jun 2020 [monthly]

    Recruiting PHASE2

  20. Feb 2020 — Apr 2020 [monthly]

    Recruiting PHASE2

    Status: Not Yet Recruiting → Recruiting

  21. Dec 2019 — Feb 2020 [monthly]

    Not Yet Recruiting PHASE2

  22. Aug 2019 — Dec 2019 [monthly]

    Not Yet Recruiting PHASE2

  23. Jul 2019 — Aug 2019 [monthly]

    Not Yet Recruiting PHASE2

  24. Jun 2019 — Jul 2019 [monthly]

    Not Yet Recruiting PHASE2

  25. Apr 2019 — Jun 2019 [monthly]

    Not Yet Recruiting PHASE2

  26. Mar 2019 — Apr 2019 [monthly]

    Not Yet Recruiting PHASE2

  27. Feb 2019 — Mar 2019 [monthly]

    Not Yet Recruiting PHASE2

  28. Jan 2019 — Feb 2019 [monthly]

    Not Yet Recruiting PHASE2

  29. Dec 2018 — Jan 2019 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • National Institute of Allergy and Infectious Diseases (NIAID)
  • ViiV Healthcare
Data source: National Institute of Allergy and Infectious Diseases (NIAID)

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Aurora, United States , Baltimore, United States , Birmingham, United States , Chapel Hill, United States , Chicago, United States , Cincinnati, United States , Columbus, United States , New York, United States , Newark, United States , Philadelphia, United States and 6 more locations