deltatrials
Completed PHASE1 INTERVENTIONAL 2-arm NCT03506854

Study of ISIS 681257 in Patients With Renal Impairment Compared to Healthy Patients

Phase 1, Multicenter, Open-Label, Parallel Group Adaptive Pharmacokinetic Single Dose Study Of ISIS 681257 Subcutaneous Injections In Male And Female Subjects With Normal And Impaired Renal Function

Sponsor: Akcea Therapeutics

Interventions ISIS 681257
Updated 7 times since 2018 Last updated: May 20, 2019 Started: Mar 20, 2018 Primary completion: Oct 11, 2018 Completion: Oct 11, 2018
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE1 clinical study on Renal Impairment, this trial is completed. The trial is conducted by Akcea Therapeutics and has accumulated 7 data snapshots since 2018. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

~May 2018 – ~Jun 2018 · 31 days · monthly snapshotRecruiting~Jun 2018 – ~Nov 2018 · 5 months · monthly snapshotRecruiting~Nov 2018 – ~Jun 2019 · 7 months · monthly snapshotRecruiting~Jun 2019 – ~Jan 2021 · 19 months · monthly snapshotCompleted~Jan 2021 – ~Jul 2024 · 42 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – present · 22 months · monthly snapshotCompleted

Change History

7 versions recorded
  1. Sep 2024 — Present [monthly]

    Completed PHASE1

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1

  3. Jan 2021 — Jul 2024 [monthly]

    Completed PHASE1

  4. Jun 2019 — Jan 2021 [monthly]

    Completed PHASE1

    Status: RecruitingCompleted

  5. Nov 2018 — Jun 2019 [monthly]

    Recruiting PHASE1

Show 2 earlier versions
  1. Jun 2018 — Nov 2018 [monthly]

    Recruiting PHASE1

  2. May 2018 — Jun 2018 [monthly]

    Recruiting PHASE1

    First recorded

Mar 2018

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Akcea Therapeutics
  • Ionis Pharmaceuticals, Inc.
Data source: Akcea Therapeutics

For direct contact, visit the study record on ClinicalTrials.gov .