deltatrials
Suspended OBSERVATIONAL NCT03513549

Observational Study Evaluating the Safety of ADASUVE® in Agitation Associated With Schizophrenia or Bipolar I Disorder

A Postmarketing Observational Study to Evaluate the Safety of ADASUVE® (STACCATO® Loxapine for Inhalation) in Patients With Agitation Associated With Schizophrenia or Bipolar I Disorder

Sponsor: Alexza Pharmaceuticals, Inc.

Interventions Loxapine 10 MG
Updated 9 times since 2018 Last updated: Oct 20, 2025 Started: Nov 4, 2014 Primary completion: Feb 28, 2027 Completion: Sep 30, 2027
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Suspended

Suspended due to low patient enrollment resulting from low commercial usage of Adasuve. Study continuation is impractical. Alexza has been in discussions with FDA on this matter.

This observational or N/A phase trial investigates Agitation,Psychomotor and is currently suspended. Alexza Pharmaceuticals, Inc. leads this study, which shows 9 recorded versions since 2014 — indicating limited longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Jun 2018 – ~Aug 2019 · 14 months · monthly snapshotRecruiting~Aug 2019 – ~Nov 2020 · 15 months · monthly snapshotRecruiting~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshotRecruiting~Jan 2021 – ~Nov 2022 · 22 months · monthly snapshotRecruiting~Nov 2022 – ~Jul 2024 · 20 months · monthly snapshotUnknown Status~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotUnknown~Sep 2024 – ~Nov 2025 · 14 months · monthly snapshotUnknown~Nov 2025 – ~Feb 2026 · 3 months · monthly snapshotSuspended~Feb 2026 – present · 5 months · monthly snapshotSuspended

Change History

9 versions recorded
  1. Feb 2026 — Present [monthly]

    Suspended

  2. Nov 2025 — Feb 2026 [monthly]

    Suspended

    Status: UnknownSuspended

  3. Sep 2024 — Nov 2025 [monthly]

    Unknown

  4. Jul 2024 — Sep 2024 [monthly]

    Unknown

    Status: Unknown StatusUnknown

  5. Nov 2022 — Jul 2024 [monthly]

    Unknown Status

    Status: RecruitingUnknown Status

Show 4 earlier versions
  1. Jan 2021 — Nov 2022 [monthly]

    Recruiting

  2. Nov 2020 — Jan 2021 [monthly]

    Recruiting

  3. Aug 2019 — Nov 2020 [monthly]

    Recruiting

  4. Jun 2018 — Aug 2019 [monthly]

    Recruiting

    First recorded

Nov 2014

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Alexza Pharmaceuticals, Inc.
  • Pharmaceutical Research Associates
Data source: Nova Pneuma Inc.

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations