deltatrials
Completed PHASE2 INTERVENTIONAL 1-arm NCT03520842

Regorafenib and Methotrexate in Treating Participants With Recurrent or Metastatic KRAS Mutated Non-Small Cell Lung Cancer

Study of Regorafenib in Combination With Oral Methotrexate for KRAS Mutated Non-Small Cell Lung Cancer (NSCLC)

Sponsor: Stanford University

Updated 12 times since 2018 Last updated: Jul 12, 2023 Started: Aug 14, 2018 Primary completion: Jun 15, 2022 Completion: Jun 15, 2022
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE2 trial investigates KRAS Gene Mutation and Metastatic Malignant Neoplasm in the Brain and is currently completed. Stanford University leads this study, which shows 12 recorded versions since 2018 — indicating substantial longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Jun 2018 – ~Sep 2018 · 3 months · monthly snapshotNot Yet Recruiting~Sep 2018 – ~May 2019 · 8 months · monthly snapshotRecruiting~May 2019 – ~Dec 2019 · 7 months · monthly snapshotSuspended~Dec 2019 – ~Jul 2020 · 7 months · monthly snapshotRecruiting~Jul 2020 – ~Jan 2021 · 6 months · monthly snapshotRecruiting~Jan 2021 – ~Nov 2021 · 10 months · monthly snapshotRecruiting~Nov 2021 – ~Feb 2022 · 3 months · monthly snapshotRecruiting~Feb 2022 – ~Mar 2022 · 28 days · monthly snapshotRecruiting~Mar 2022 – ~Sep 2023 · 18 months · monthly snapshotActive Not Recruiting~Sep 2023 – ~Jul 2024 · 10 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – present · 24 months · monthly snapshotCompleted

Change History

12 versions recorded
  1. Sep 2024 — Present [monthly]

    Completed PHASE2

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE2

  3. Sep 2023 — Jul 2024 [monthly]

    Completed PHASE2

    Status: Active Not RecruitingCompleted

  4. Mar 2022 — Sep 2023 [monthly]

    Active Not Recruiting PHASE2

    Status: RecruitingActive Not Recruiting

  5. Feb 2022 — Mar 2022 [monthly]

    Recruiting PHASE2

Show 7 earlier versions
  1. Nov 2021 — Feb 2022 [monthly]

    Recruiting PHASE2

  2. Jan 2021 — Nov 2021 [monthly]

    Recruiting PHASE2

  3. Jul 2020 — Jan 2021 [monthly]

    Recruiting PHASE2

  4. Dec 2019 — Jul 2020 [monthly]

    Recruiting PHASE2

    Status: SuspendedRecruiting

  5. May 2019 — Dec 2019 [monthly]

    Suspended PHASE2

    Status: RecruitingSuspended

  6. Sep 2018 — May 2019 [monthly]

    Recruiting PHASE2

    Status: Not Yet RecruitingRecruiting

  7. Jun 2018 — Sep 2018 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Stanford University
Data source: Stanford University

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations