deltatrials
Completed PHASE1 INTERVENTIONAL 2-arm NCT03555539

Study of Danicopan in Participants With Hepatic Impairment

A Phase 1, 2-Part, Open-Label, Single-Dose, Parallel Group Study to Determine the Effect of Hepatic Impairment on the Safety, Tolerability, and Pharmacokinetics of ACH-0144471 in Adult Subjects

Sponsor: Achillion, a wholly owned subsidiary of Alexion

Interventions Danicopan
Updated 10 times since 2018 Last updated: Aug 16, 2021 Started: May 1, 2018 Primary completion: Sep 21, 2018 Completion: Sep 21, 2018
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT03555539, this PHASE1 trial focuses on Hepatic Impairment and remains completed. Sponsored by Achillion, a wholly owned subsidiary of Alexion, it has been updated 10 times since 2018, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Jul 2018 – ~Sep 2018 · 2 months · monthly snapshotRecruiting~Sep 2018 – ~Feb 2019 · 5 months · monthly snapshotRecruiting~Feb 2019 – ~Jun 2020 · 16 months · monthly snapshotCompleted~Jun 2020 – ~Jan 2021 · 7 months · monthly snapshotCompleted~Jan 2021 – ~Sep 2021 · 8 months · monthly snapshotCompleted~Sep 2021 – ~Apr 2023 · 19 months · monthly snapshotCompleted~Apr 2023 – ~Nov 2023 · 7 months · monthly snapshotCompleted~Nov 2023 – ~Jul 2024 · 8 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – present · 23 months · monthly snapshotCompleted

Change History

10 versions recorded
  1. Sep 2024 — Present [monthly]

    Completed PHASE1

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1

  3. Nov 2023 — Jul 2024 [monthly]

    Completed PHASE1

  4. Apr 2023 — Nov 2023 [monthly]

    Completed PHASE1

  5. Sep 2021 — Apr 2023 [monthly]

    Completed PHASE1

Show 5 earlier versions
  1. Jan 2021 — Sep 2021 [monthly]

    Completed PHASE1

  2. Jun 2020 — Jan 2021 [monthly]

    Completed PHASE1

  3. Feb 2019 — Jun 2020 [monthly]

    Completed PHASE1

    Status: RecruitingCompleted

  4. Sep 2018 — Feb 2019 [monthly]

    Recruiting PHASE1

  5. Jul 2018 — Sep 2018 [monthly]

    Recruiting PHASE1

    First recorded

May 2018

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Achillion, a wholly owned subsidiary of Alexion
  • Alexion Pharmaceuticals, Inc.
Data source: Alexion Pharmaceuticals, Inc.

For direct contact, visit the study record on ClinicalTrials.gov .