deltatrials
Completed PHASE3 INTERVENTIONAL 1-arm NCT03559699

A Study Evaluating the Efficacy and Safety of AG-348 in Regularly Transfused Adult Participants With Pyruvate Kinase Deficiency (PKD)

An Open-Label Study To Evaluate the Efficacy and Safety of AG-348 in Regularly Transfused Adult Subjects With Pyruvate Kinase (PK) Deficiency

Sponsor: Agios Pharmaceuticals, Inc.

Interventions AG-348
Updated 29 times since 2018 Last updated: Dec 14, 2021 Started: Jun 26, 2018 Primary completion: Nov 12, 2020 Completion: Nov 12, 2020
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE3 clinical study on Anemia, Hemolytic and Pyruvate Kinase Deficiency, this trial is completed. The trial is conducted by Agios Pharmaceuticals, Inc. and has accumulated 29 data snapshots since 2018. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

~Jul 2018 – ~Aug 2018 · 31 days · monthly snapshot~Aug 2018 – ~Jan 2019 · 5 months · monthly snapshot~Jan 2019 – ~Feb 2019 · 31 days · monthly snapshot~Feb 2019 – ~Mar 2019 · 28 days · monthly snapshot~Mar 2019 – ~Jun 2019 · 3 months · monthly snapshot~Jun 2019 – ~Jul 2019 · 30 days · monthly snapshot~Jul 2019 – ~Aug 2019 · 31 days · monthly snapshot~Aug 2019 – ~Sep 2019 · 31 days · monthly snapshot~Sep 2019 – ~Oct 2019 · 30 days · monthly snapshot~Oct 2019 – ~Nov 2019 · 31 days · monthly snapshot~Nov 2019 – ~Dec 2019 · 30 days · monthly snapshot~Dec 2019 – ~Jan 2020 · 31 days · monthly snapshot~Jan 2020 – ~Feb 2020 · 31 days · monthly snapshot~Feb 2020 – ~Mar 2020 · 29 days · monthly snapshot~Mar 2020 – ~Apr 2020 · 31 days · monthly snapshot~Apr 2020 – ~May 2020 · 30 days · monthly snapshot~May 2020 – ~Jun 2020 · 31 days · monthly snapshot~Jun 2020 – ~Jul 2020 · 30 days · monthly snapshot~Jul 2020 – ~Aug 2020 · 31 days · monthly snapshot~Aug 2020 – ~Sep 2020 · 31 days · monthly snapshot~Sep 2020 – ~Oct 2020 · 30 days · monthly snapshot~Oct 2020 – ~Nov 2020 · 31 days · monthly snapshot~Nov 2020 – ~Dec 2020 · 30 days · monthly snapshot~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshot~Jan 2021 – ~Jan 2022 · 12 months · monthly snapshot~Jan 2022 – ~Jul 2024 · 30 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – present · 11 months · monthly snapshot

Change History

29 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE3

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE3

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE3

  4. Jan 2022 — Jul 2024 [monthly]

    Completed PHASE3

  5. Jan 2021 — Jan 2022 [monthly]

    Completed PHASE3

    Status: Active Not RecruitingCompleted

Show 24 earlier versions
  1. Dec 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE3

  2. Nov 2020 — Dec 2020 [monthly]

    Active Not Recruiting PHASE3

  3. Oct 2020 — Nov 2020 [monthly]

    Active Not Recruiting PHASE3

  4. Sep 2020 — Oct 2020 [monthly]

    Active Not Recruiting PHASE3

  5. Aug 2020 — Sep 2020 [monthly]

    Active Not Recruiting PHASE3

  6. Jul 2020 — Aug 2020 [monthly]

    Active Not Recruiting PHASE3

  7. Jun 2020 — Jul 2020 [monthly]

    Active Not Recruiting PHASE3

  8. May 2020 — Jun 2020 [monthly]

    Active Not Recruiting PHASE3

  9. Apr 2020 — May 2020 [monthly]

    Active Not Recruiting PHASE3

  10. Mar 2020 — Apr 2020 [monthly]

    Active Not Recruiting PHASE3

    Status: RecruitingActive Not Recruiting

  11. Feb 2020 — Mar 2020 [monthly]

    Recruiting PHASE3

  12. Jan 2020 — Feb 2020 [monthly]

    Recruiting PHASE3

  13. Dec 2019 — Jan 2020 [monthly]

    Recruiting PHASE3

  14. Nov 2019 — Dec 2019 [monthly]

    Recruiting PHASE3

  15. Oct 2019 — Nov 2019 [monthly]

    Recruiting PHASE3

  16. Sep 2019 — Oct 2019 [monthly]

    Recruiting PHASE3

  17. Aug 2019 — Sep 2019 [monthly]

    Recruiting PHASE3

  18. Jul 2019 — Aug 2019 [monthly]

    Recruiting PHASE3

  19. Jun 2019 — Jul 2019 [monthly]

    Recruiting PHASE3

  20. Mar 2019 — Jun 2019 [monthly]

    Recruiting PHASE3

  21. Feb 2019 — Mar 2019 [monthly]

    Recruiting PHASE3

  22. Jan 2019 — Feb 2019 [monthly]

    Recruiting PHASE3

  23. Aug 2018 — Jan 2019 [monthly]

    Recruiting PHASE3

  24. Jul 2018 — Aug 2018 [monthly]

    Recruiting PHASE3

    First recorded

Jun 2018

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Agios Pharmaceuticals, Inc.
Data source: Agios Pharmaceuticals, Inc.

For direct contact, visit the study record on ClinicalTrials.gov .