deltatrials
Active Not Recruiting PHASE1 INTERVENTIONAL 1-arm NCT03589339

NBTXR3 Activated by Radiotherapy for Patients With Advanced Cancers Treated With An Anti-PD-1 Therapy

A Phase I Dose Escalation / Dose Expansion Study of NBTXR3 Activated by Radiotherapy for Patients With Advanced Cancers Treated With An Anti-PD-1 Therapy

Sponsor: Nanobiotix

Updated 17 times since 2018 Last updated: Oct 23, 2025 Started: Jan 16, 2019 Primary completion: Apr 30, 2027 Completion: Aug 30, 2027
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE1 clinical study on Immunotherapy and Metastasis From Malignant Melanoma of Skin (Disorder), this trial is ongoing. The trial is conducted by Nanobiotix and has accumulated 17 data snapshots since 2019. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Aug 2018 – ~Feb 2020 · 18 months · monthly snapshot~Feb 2020 – ~Nov 2020 · 9 months · monthly snapshot~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshot~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshot~Feb 2021 – ~Apr 2022 · 14 months · monthly snapshot~Apr 2022 – ~Jul 2022 · 3 months · monthly snapshot~Jul 2022 – ~Sep 2022 · 2 months · monthly snapshot~Sep 2022 – ~Nov 2022 · 2 months · monthly snapshot~Nov 2022 – ~Feb 2023 · 3 months · monthly snapshot~Feb 2023 – ~Jan 2024 · 11 months · monthly snapshot~Jan 2024 – ~Mar 2024 · 2 months · monthly snapshot~Mar 2024 – ~Apr 2024 · 31 days · monthly snapshot~Apr 2024 – ~Jul 2024 · 3 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Feb 2025 · 5 months · monthly snapshot~Feb 2025 – ~Nov 2025 · 9 months · monthly snapshot~Nov 2025 – present · 8 months · monthly snapshot

Change History

17 versions recorded
  1. Nov 2025 — Present [monthly]

    Active Not Recruiting PHASE1

    Status: RecruitingActive Not Recruiting

  2. Feb 2025 — Nov 2025 [monthly]

    Recruiting PHASE1

  3. Sep 2024 — Feb 2025 [monthly]

    Recruiting PHASE1

  4. Jul 2024 — Sep 2024 [monthly]

    Recruiting PHASE1

  5. Apr 2024 — Jul 2024 [monthly]

    Recruiting PHASE1

Show 12 earlier versions
  1. Mar 2024 — Apr 2024 [monthly]

    Recruiting PHASE1

  2. Jan 2024 — Mar 2024 [monthly]

    Recruiting PHASE1

  3. Feb 2023 — Jan 2024 [monthly]

    Recruiting PHASE1

  4. Nov 2022 — Feb 2023 [monthly]

    Recruiting PHASE1

  5. Sep 2022 — Nov 2022 [monthly]

    Recruiting PHASE1

  6. Jul 2022 — Sep 2022 [monthly]

    Recruiting PHASE1

  7. Apr 2022 — Jul 2022 [monthly]

    Recruiting PHASE1

  8. Feb 2021 — Apr 2022 [monthly]

    Recruiting PHASE1

  9. Jan 2021 — Feb 2021 [monthly]

    Recruiting PHASE1

  10. Nov 2020 — Jan 2021 [monthly]

    Recruiting PHASE1

  11. Feb 2020 — Nov 2020 [monthly]

    Recruiting PHASE1

    Status: Not Yet RecruitingRecruiting · Phase: PHASE1_PHASE2PHASE1

  12. Aug 2018 — Feb 2020 [monthly]

    Not Yet Recruiting PHASE1_PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Nanobiotix
Data source: Nanobiotix

For direct contact, visit the study record on ClinicalTrials.gov .