deltatrials
Completed PHASE4 INTERVENTIONAL 2-arm NCT03596450

Long Term Comparative Effectiveness of Once Weekly Semaglutide Versus Standard of Care in a Real World Adult US Population With Type 2 Diabetes - a Randomized Pragmatic Trial

Long Term Comparative Effectiveness of Once Weekly Semaglutide Versus Standard of Care in a Real World Adult US Population With Type 2 Diabetes - a Randomized Pragmatic Clinical Trial

Sponsor: Novo Nordisk A/S

Conditions Diabetes Mellitus, Type 2
Interventions Semaglutide Standard of care
Updated 37 times since 2018 Last updated: Jun 7, 2024 Started: Jul 13, 2018 Primary completion: Jun 9, 2022 Completion: Jun 9, 2023
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT03596450, this PHASE4 trial focuses on Diabetes Mellitus, Type 2 and remains completed. Sponsored by Novo Nordisk A/S, it has been updated 37 times since 2018, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Aug 2018 – ~Sep 2018 · 31 days · monthly snapshot~Sep 2018 – ~Jan 2019 · 4 months · monthly snapshot~Jan 2019 – ~Feb 2019 · 31 days · monthly snapshot~Feb 2019 – ~Mar 2019 · 28 days · monthly snapshot~Mar 2019 – ~Apr 2019 · 31 days · monthly snapshot~Apr 2019 – ~May 2019 · 30 days · monthly snapshot~May 2019 – ~Jun 2019 · 31 days · monthly snapshot~Jun 2019 – ~Jul 2019 · 30 days · monthly snapshot~Jul 2019 – ~Aug 2019 · 31 days · monthly snapshot~Aug 2019 – ~Sep 2019 · 31 days · monthly snapshot~Sep 2019 – ~Oct 2019 · 30 days · monthly snapshot~Oct 2019 – ~Nov 2019 · 31 days · monthly snapshot~Nov 2019 – ~Dec 2019 · 30 days · monthly snapshot~Dec 2019 – ~Jan 2020 · 31 days · monthly snapshot~Jan 2020 – ~Feb 2020 · 31 days · monthly snapshot~Feb 2020 – ~Apr 2020 · 2 months · monthly snapshot~Apr 2020 – ~Dec 2020 · 8 months · monthly snapshot~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshot~Jan 2021 – ~Sep 2021 · 8 months · monthly snapshot~Sep 2021 – ~Oct 2021 · 30 days · monthly snapshot~Oct 2021 – ~Nov 2021 · 31 days · monthly snapshot~Nov 2021 – ~Dec 2021 · 30 days · monthly snapshot~Dec 2021 – ~Apr 2022 · 4 months · monthly snapshot~Apr 2022 – ~Jul 2022 · 3 months · monthly snapshot~Jul 2022 – ~Sep 2022 · 2 months · monthly snapshot~Sep 2022 – ~Nov 2022 · 2 months · monthly snapshot~Nov 2022 – ~Dec 2022 · 30 days · monthly snapshot~Dec 2022 – ~Mar 2023 · 3 months · monthly snapshot~Mar 2023 – ~May 2023 · 2 months · monthly snapshot~May 2023 – ~Jun 2023 · 31 days · monthly snapshot~Jun 2023 – ~Sep 2023 · 3 months · monthly snapshot~Sep 2023 – ~Dec 2023 · 3 months · monthly snapshot~Dec 2023 – ~Jul 2024 · 7 months · monthly snapshot~Jul 2024 – ~Aug 2024 · 31 days · monthly snapshot~Aug 2024 – ~Sep 2024 · 31 days · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – present · 10 months · monthly snapshot

Change History

37 versions recorded

  1. Sep 2025 — Present [monthly]

    Completed PHASE4

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE4

  3. Aug 2024 — Sep 2024 [monthly]

    Completed PHASE4

  4. Jul 2024 — Aug 2024 [monthly]

    Completed PHASE4

  5. Dec 2023 — Jul 2024 [monthly]

    Completed PHASE4

▶ Show 32 earlier versions

  1. Sep 2023 — Dec 2023 [monthly]

    Completed PHASE4

    Status: Active Not Recruiting → Completed

  2. Jun 2023 — Sep 2023 [monthly]

    Active Not Recruiting PHASE4

  3. May 2023 — Jun 2023 [monthly]

    Active Not Recruiting PHASE4

  4. Mar 2023 — May 2023 [monthly]

    Active Not Recruiting PHASE4

  5. Dec 2022 — Mar 2023 [monthly]

    Active Not Recruiting PHASE4

  6. Nov 2022 — Dec 2022 [monthly]

    Active Not Recruiting PHASE4

  7. Sep 2022 — Nov 2022 [monthly]

    Active Not Recruiting PHASE4

  8. Jul 2022 — Sep 2022 [monthly]

    Active Not Recruiting PHASE4

  9. Apr 2022 — Jul 2022 [monthly]

    Active Not Recruiting PHASE4

  10. Dec 2021 — Apr 2022 [monthly]

    Active Not Recruiting PHASE4

  11. Nov 2021 — Dec 2021 [monthly]

    Active Not Recruiting PHASE4

  12. Oct 2021 — Nov 2021 [monthly]

    Active Not Recruiting PHASE4

  13. Sep 2021 — Oct 2021 [monthly]

    Active Not Recruiting PHASE4

    Status: Recruiting → Active Not Recruiting

  14. Jan 2021 — Sep 2021 [monthly]

    Recruiting PHASE4

  15. Dec 2020 — Jan 2021 [monthly]

    Recruiting PHASE4

  16. Apr 2020 — Dec 2020 [monthly]

    Recruiting PHASE4

  17. Feb 2020 — Apr 2020 [monthly]

    Recruiting PHASE4

  18. Jan 2020 — Feb 2020 [monthly]

    Recruiting PHASE4

  19. Dec 2019 — Jan 2020 [monthly]

    Recruiting PHASE4

  20. Nov 2019 — Dec 2019 [monthly]

    Recruiting PHASE4

  21. Oct 2019 — Nov 2019 [monthly]

    Recruiting PHASE4

  22. Sep 2019 — Oct 2019 [monthly]

    Recruiting PHASE4

  23. Aug 2019 — Sep 2019 [monthly]

    Recruiting PHASE4

  24. Jul 2019 — Aug 2019 [monthly]

    Recruiting PHASE4

  25. Jun 2019 — Jul 2019 [monthly]

    Recruiting PHASE4

  26. May 2019 — Jun 2019 [monthly]

    Recruiting PHASE4

  27. Apr 2019 — May 2019 [monthly]

    Recruiting PHASE4

  28. Mar 2019 — Apr 2019 [monthly]

    Recruiting PHASE4

  29. Feb 2019 — Mar 2019 [monthly]

    Recruiting PHASE4

  30. Jan 2019 — Feb 2019 [monthly]

    Recruiting PHASE4

  31. Sep 2018 — Jan 2019 [monthly]

    Recruiting PHASE4

    Status: Not Yet Recruiting → Recruiting

  32. Aug 2018 — Sep 2018 [monthly]

    Not Yet Recruiting PHASE4

    First recorded

Jul 2018

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Novo Nordisk A/S
Data source: Novo Nordisk A/S

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Albany, United States , Anderson, United States , Arlington, United States , Ashland, United States , Athens, United States , Atlanta, United States , Augusta, United States , Avon, United States , Belfast, United States , Berne, United States and 94 more locations