Completed PHASE2 INTERVENTIONAL 7-arm NCT03596905

Efficacy and Safety of Plecanatide in Children 6 to <18 Years With Irritable Bowel Syndrome With Constipation (IBS-C) ((IBS-C))

A Randomized, Double-blind, Placebo-Controlled, Dose Ranging, Parallel-Group Study of the Efficacy and Safety of Plecanatide in Children 6 to <18 Years of Age With Irritable Bowel Syndrome With Constipation (IBS-C)

Sponsor: Bausch Health Americas, Inc.

Conditions Irritable Bowel Syndrome With Constipation

Interventions Matching placebo Plecanatide

Updated 13 times since 2018 Last updated: Dec 10, 2025 Started: Jun 30, 2018 Primary completion: Nov 25, 2024 Completion: Nov 25, 2024

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE2 clinical study on Irritable Bowel Syndrome With Constipation, this trial is completed. The trial is conducted by Bausch Health Americas, Inc. and has accumulated 13 data snapshots since 2018. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

Change History

13 versions recorded

Jan 2026 — Present [monthly]

Completed PHASE2
Sep 2025 — Jan 2026 [monthly]

Completed PHASE2

Status: Unknown → Completed
Mar 2025 — Sep 2025 [monthly]

Unknown PHASE2

Status: Recruiting → Unknown
Sep 2024 — Mar 2025 [monthly]

Recruiting PHASE2
Jul 2024 — Sep 2024 [monthly]

Recruiting PHASE2

▶ Show 8 earlier versions

Mar 2023 — Jul 2024 [monthly]

Recruiting PHASE2
Feb 2022 — Mar 2023 [monthly]

Recruiting PHASE2
Feb 2021 — Feb 2022 [monthly]

Recruiting PHASE2
Jan 2021 — Feb 2021 [monthly]

Recruiting PHASE2
Apr 2020 — Jan 2021 [monthly]

Recruiting PHASE2
Jun 2019 — Apr 2020 [monthly]

Recruiting PHASE2
Feb 2019 — Jun 2019 [monthly]

Recruiting PHASE2
Aug 2018 — Feb 2019 [monthly]

Recruiting PHASE2

First recorded

Jun 2018

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Bausch Health Americas, Inc.

Data source: Bausch Health Americas, Inc.

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Akron, United States , Atlanta, United States , Aurora, United States , Austin, United States , Bellevue, United States , Bowling Green, United States , Cedar Park, United States , Cleveland, United States , Corona, United States , Covington, United States and 21 more locations