deltatrials
Completed PHASE3 INTERVENTIONAL 3-arm NCT03607422

A Study to Evaluate Upadacitinib in Adolescents and Adults With Moderate to Severe Atopic Dermatitis (Measure Up 2)

A Phase 3 Randomized, Placebo-Controlled, Double-Blind Study to Evaluate Upadacitinib in Adolescent and Adult Subjects With Moderate to Severe Atopic Dermatitis

Sponsor: AbbVie

Conditions Atopic Dermatitis
Interventions Placebo for Upadacitinib Upadacitinib
Updated 35 times since 2018 Last updated: Nov 18, 2025 Started: Jul 27, 2018 Primary completion: Mar 11, 2021 Completion: Nov 11, 2025
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE3 trial investigates Atopic Dermatitis and is currently completed. AbbVie leads this study, which shows 35 recorded versions since 2018 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Aug 2018 – ~Sep 2018 · 31 days · monthly snapshot~Sep 2018 – ~Oct 2018 · 30 days · monthly snapshot~Oct 2018 – ~Nov 2018 · 31 days · monthly snapshot~Nov 2018 – ~Jan 2019 · 2 months · monthly snapshot~Jan 2019 – ~Feb 2019 · 31 days · monthly snapshot~Feb 2019 – ~Mar 2019 · 28 days · monthly snapshot~Mar 2019 – ~Apr 2019 · 31 days · monthly snapshot~Apr 2019 – ~May 2019 · 30 days · monthly snapshot~May 2019 – ~Jun 2019 · 31 days · monthly snapshot~Jun 2019 – ~Jul 2019 · 30 days · monthly snapshot~Jul 2019 – ~Aug 2019 · 31 days · monthly snapshot~Aug 2019 – ~Sep 2019 · 31 days · monthly snapshot~Sep 2019 – ~Oct 2019 · 30 days · monthly snapshot~Oct 2019 – ~Nov 2019 · 31 days · monthly snapshot~Nov 2019 – ~Dec 2019 · 30 days · monthly snapshot~Dec 2019 – ~Jan 2020 · 31 days · monthly snapshot~Jan 2020 – ~Feb 2020 · 31 days · monthly snapshot~Feb 2020 – ~Mar 2020 · 29 days · monthly snapshot~Mar 2020 – ~Jun 2020 · 3 months · monthly snapshot~Jun 2020 – ~Jul 2020 · 30 days · monthly snapshot~Jul 2020 – ~Aug 2020 · 31 days · monthly snapshot~Aug 2020 – ~Sep 2020 · 31 days · monthly snapshot~Sep 2020 – ~Nov 2020 · 2 months · monthly snapshot~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshot~Jan 2021 – ~Jun 2021 · 5 months · monthly snapshot~Jun 2021 – ~Oct 2021 · 4 months · monthly snapshot~Oct 2021 – ~Apr 2022 · 6 months · monthly snapshot~Apr 2022 – ~Jul 2023 · 15 months · monthly snapshot~Jul 2023 – ~Apr 2024 · 9 months · monthly snapshot~Apr 2024 – ~Jul 2024 · 3 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~May 2025 · 8 months · monthly snapshot~May 2025 – ~Sep 2025 · 4 months · monthly snapshot~Sep 2025 – ~Jan 2026 · 4 months · monthly snapshot~Jan 2026 – present · 8 months · monthly snapshot

Change History

35 versions recorded

  1. Jan 2026 — Present [monthly]

    Completed PHASE3

    Status: Active Not Recruiting → Completed

  2. Sep 2025 — Jan 2026 [monthly]

    Active Not Recruiting PHASE3

  3. May 2025 — Sep 2025 [monthly]

    Active Not Recruiting PHASE3

  4. Sep 2024 — May 2025 [monthly]

    Active Not Recruiting PHASE3

  5. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE3

▶ Show 30 earlier versions

  1. Apr 2024 — Jul 2024 [monthly]

    Active Not Recruiting PHASE3

  2. Jul 2023 — Apr 2024 [monthly]

    Active Not Recruiting PHASE3

  3. Apr 2022 — Jul 2023 [monthly]

    Active Not Recruiting PHASE3

  4. Oct 2021 — Apr 2022 [monthly]

    Active Not Recruiting PHASE3

  5. Jun 2021 — Oct 2021 [monthly]

    Active Not Recruiting PHASE3

  6. Jan 2021 — Jun 2021 [monthly]

    Active Not Recruiting PHASE3

    Status: Recruiting → Active Not Recruiting

  7. Nov 2020 — Jan 2021 [monthly]

    Recruiting PHASE3

  8. Sep 2020 — Nov 2020 [monthly]

    Recruiting PHASE3

  9. Aug 2020 — Sep 2020 [monthly]

    Recruiting PHASE3

  10. Jul 2020 — Aug 2020 [monthly]

    Recruiting PHASE3

  11. Jun 2020 — Jul 2020 [monthly]

    Recruiting PHASE3

  12. Mar 2020 — Jun 2020 [monthly]

    Recruiting PHASE3

  13. Feb 2020 — Mar 2020 [monthly]

    Recruiting PHASE3

  14. Jan 2020 — Feb 2020 [monthly]

    Recruiting PHASE3

  15. Dec 2019 — Jan 2020 [monthly]

    Recruiting PHASE3

  16. Nov 2019 — Dec 2019 [monthly]

    Recruiting PHASE3

  17. Oct 2019 — Nov 2019 [monthly]

    Recruiting PHASE3

  18. Sep 2019 — Oct 2019 [monthly]

    Recruiting PHASE3

  19. Aug 2019 — Sep 2019 [monthly]

    Recruiting PHASE3

  20. Jul 2019 — Aug 2019 [monthly]

    Recruiting PHASE3

  21. Jun 2019 — Jul 2019 [monthly]

    Recruiting PHASE3

  22. May 2019 — Jun 2019 [monthly]

    Recruiting PHASE3

  23. Apr 2019 — May 2019 [monthly]

    Recruiting PHASE3

  24. Mar 2019 — Apr 2019 [monthly]

    Recruiting PHASE3

  25. Feb 2019 — Mar 2019 [monthly]

    Recruiting PHASE3

  26. Jan 2019 — Feb 2019 [monthly]

    Recruiting PHASE3

  27. Nov 2018 — Jan 2019 [monthly]

    Recruiting PHASE3

  28. Oct 2018 — Nov 2018 [monthly]

    Recruiting PHASE3

  29. Sep 2018 — Oct 2018 [monthly]

    Recruiting PHASE3

    Status: Not Yet Recruiting → Recruiting

  30. Aug 2018 — Sep 2018 [monthly]

    Not Yet Recruiting PHASE3

    First recorded

Jul 2018

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • AbbVie
Data source: AbbVie

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Aarhus N, Denmark , Albany, United States , Albuquerque, United States , Alkmaar, Netherlands , Ann Arbor, United States , Ansan, South Korea , Antony, France , Arlington, United States , Athens, Greece , Aventura, United States and 151 more locations