deltatrials
Completed PHASE3 INTERVENTIONAL 2-arm NCT03616899

Safety and Efficacy of KPI-121 in Subjects With DED (STRIDE 3)

A Phase 3, Double-masked, Randomized, Controlled Study of KPI-121 0.25% Ophthalmic Suspension Compared to Vehicle In Subjects With Dry Eye Disease (STRIDE 3)

Sponsor: Kala Pharmaceuticals, Inc.

Updated 14 times since 2018 Last updated: Mar 9, 2021 Started: Jul 10, 2018 Primary completion: Feb 5, 2020 Completion: Feb 5, 2020
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE3 trial investigates Kerato Conjunctivitis Sicca and is currently completed. Kala Pharmaceuticals, Inc. leads this study, which shows 14 recorded versions since 2018 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Sep 2018 – ~Nov 2018 · 2 months · monthly snapshot~Nov 2018 – ~Apr 2019 · 5 months · monthly snapshot~Apr 2019 – ~May 2019 · 30 days · monthly snapshot~May 2019 – ~Aug 2019 · 3 months · monthly snapshot~Aug 2019 – ~Apr 2020 · 8 months · monthly snapshot~Apr 2020 – ~Jun 2020 · 2 months · monthly snapshot~Jun 2020 – ~Jan 2021 · 7 months · monthly snapshot~Jan 2021 – ~May 2021 · 4 months · monthly snapshot~May 2021 – ~Dec 2022 · 19 months · monthly snapshot~Dec 2022 – ~Jan 2023 · 31 days · monthly snapshot~Jan 2023 – ~Jul 2024 · 18 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – present · 10 months · monthly snapshot

Change History

14 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE3

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE3

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE3

  4. Jan 2023 — Jul 2024 [monthly]

    Completed PHASE3

  5. Dec 2022 — Jan 2023 [monthly]

    Completed PHASE3

Show 9 earlier versions
  1. May 2021 — Dec 2022 [monthly]

    Completed PHASE3

  2. Jan 2021 — May 2021 [monthly]

    Completed PHASE3

  3. Jun 2020 — Jan 2021 [monthly]

    Completed PHASE3

    Status: Active Not RecruitingCompleted

  4. Apr 2020 — Jun 2020 [monthly]

    Active Not Recruiting PHASE3

    Status: RecruitingActive Not Recruiting

  5. Aug 2019 — Apr 2020 [monthly]

    Recruiting PHASE3

  6. May 2019 — Aug 2019 [monthly]

    Recruiting PHASE3

  7. Apr 2019 — May 2019 [monthly]

    Recruiting PHASE3

  8. Nov 2018 — Apr 2019 [monthly]

    Recruiting PHASE3

  9. Sep 2018 — Nov 2018 [monthly]

    Recruiting PHASE3

    First recorded

Jul 2018

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Kala Pharmaceuticals, Inc.
Data source: Kala Pharmaceuticals, Inc.

For direct contact, visit the study record on ClinicalTrials.gov .