deltatrials
Unknown PHASE1 INTERVENTIONAL 1-arm NCT03634982

Dose Escalation of RMC-4630 Monotherapy in Relapsed/Refractory Solid Tumors

A Phase 1, Open-Label, Multicenter, Dose-Escalation Study of RMC-4630 Monotherapy in Adult Participants With Relapsed/Refractory Solid Tumors

Sponsor: Revolution Medicines, Inc.

Conditions Solid Tumors
Interventions RMC-4630
Updated 21 times since 2018 Last updated: Aug 31, 2022 Started: Sep 28, 2018 Primary completion: Mar 31, 2023 Completion: May 31, 2023
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT03634982, this PHASE1 trial focuses on Solid Tumors and remains ongoing. Sponsored by Revolution Medicines, Inc., it has been updated 21 times since 2018, reflecting substantial change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Sep 2018 – ~Oct 2018 · 30 days · monthly snapshot~Oct 2018 – ~Nov 2018 · 31 days · monthly snapshot~Nov 2018 – ~Dec 2018 · 30 days · monthly snapshot~Dec 2018 – ~Jan 2019 · 31 days · monthly snapshot~Jan 2019 – ~Apr 2019 · 3 months · monthly snapshot~Apr 2019 – ~May 2019 · 30 days · monthly snapshot~May 2019 – ~Jun 2019 · 31 days · monthly snapshot~Jun 2019 – ~Aug 2019 · 2 months · monthly snapshot~Aug 2019 – ~Oct 2019 · 2 months · monthly snapshot~Oct 2019 – ~Jul 2020 · 9 months · monthly snapshot~Jul 2020 – ~Sep 2020 · 2 months · monthly snapshot~Sep 2020 – ~Nov 2020 · 2 months · monthly snapshot~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshot~Jan 2021 – ~May 2021 · 4 months · monthly snapshot~May 2021 – ~Sep 2021 · 4 months · monthly snapshot~Sep 2021 – ~Feb 2022 · 5 months · monthly snapshot~Feb 2022 – ~Sep 2022 · 7 months · monthly snapshot~Sep 2022 – ~Oct 2023 · 13 months · monthly snapshot~Oct 2023 – ~Jul 2024 · 9 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – present · 22 months · monthly snapshot

Change History

21 versions recorded
  1. Sep 2024 — Present [monthly]

    Unknown PHASE1

  2. Jul 2024 — Sep 2024 [monthly]

    Unknown PHASE1

    Status: Unknown StatusUnknown

  3. Oct 2023 — Jul 2024 [monthly]

    Unknown Status PHASE1

    Status: Active Not RecruitingUnknown Status

  4. Sep 2022 — Oct 2023 [monthly]

    Active Not Recruiting PHASE1

    Status: RecruitingActive Not Recruiting

  5. Feb 2022 — Sep 2022 [monthly]

    Recruiting PHASE1

Show 16 earlier versions
  1. Sep 2021 — Feb 2022 [monthly]

    Recruiting PHASE1

  2. May 2021 — Sep 2021 [monthly]

    Recruiting PHASE1

  3. Jan 2021 — May 2021 [monthly]

    Recruiting PHASE1

  4. Nov 2020 — Jan 2021 [monthly]

    Recruiting PHASE1

  5. Sep 2020 — Nov 2020 [monthly]

    Recruiting PHASE1

  6. Jul 2020 — Sep 2020 [monthly]

    Recruiting PHASE1

  7. Oct 2019 — Jul 2020 [monthly]

    Recruiting PHASE1

  8. Aug 2019 — Oct 2019 [monthly]

    Recruiting PHASE1

  9. Jun 2019 — Aug 2019 [monthly]

    Recruiting PHASE1

  10. May 2019 — Jun 2019 [monthly]

    Recruiting PHASE1

  11. Apr 2019 — May 2019 [monthly]

    Recruiting PHASE1

  12. Jan 2019 — Apr 2019 [monthly]

    Recruiting PHASE1

  13. Dec 2018 — Jan 2019 [monthly]

    Recruiting PHASE1

  14. Nov 2018 — Dec 2018 [monthly]

    Recruiting PHASE1

  15. Oct 2018 — Nov 2018 [monthly]

    Recruiting PHASE1

    Status: Not Yet RecruitingRecruiting

  16. Sep 2018 — Oct 2018 [monthly]

    Not Yet Recruiting PHASE1

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Revolution Medicines, Inc.
  • Sanofi
Data source: Revolution Medicines, Inc.

For direct contact, visit the study record on ClinicalTrials.gov .