deltatrials
Terminated PHASE3 INTERVENTIONAL 2-arm NCT03649659

Effectiveness of Silver Diamine Fluoride (SDF) in Arresting Cavitated Caries Lesions

Phase III RCT of the Effectiveness of Silver Diamine Fluoride in Arresting Cavitated Caries Lesions

Sponsor: NYU Langone Health

Conditions Cavities of Teeth
Interventions Placebo Silver Diamine Fluoride
Updated 17 times since 2018 Last updated: Dec 12, 2024 Started: Oct 8, 2018 Primary completion: Apr 11, 2023 Completion: Apr 27, 2023
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

The trial stopped early due to meeting interim analysis early stopping rules. Active participants at the time of the interim analyses results did complete their remaining study visits. No new participants were enrolled.

Other terminated trials from NYU Langone Health

See all terminations from NYU Langone Health

This PHASE3 trial investigates Cavities of Teeth and is currently terminated or withdrawn. NYU Langone Health leads this study, which shows 17 recorded versions since 2018 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Sep 2018 – ~Oct 2018 · 30 days · monthly snapshot~Oct 2018 – ~Nov 2018 · 31 days · monthly snapshot~Nov 2018 – ~Jun 2019 · 7 months · monthly snapshot~Jun 2019 – ~Nov 2019 · 5 months · monthly snapshot~Nov 2019 – ~May 2020 · 6 months · monthly snapshot~May 2020 – ~Aug 2020 · 3 months · monthly snapshot~Aug 2020 – ~Jan 2021 · 5 months · monthly snapshot~Jan 2021 – ~Sep 2021 · 8 months · monthly snapshot~Sep 2021 – ~Sep 2022 · 12 months · monthly snapshot~Sep 2022 – ~Nov 2022 · 2 months · monthly snapshot~Nov 2022 – ~May 2023 · 6 months · monthly snapshot~May 2023 – ~Jun 2023 · 31 days · monthly snapshot~Jun 2023 – ~May 2024 · 11 months · monthly snapshot~May 2024 – ~Jul 2024 · 2 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Feb 2025 · 5 months · monthly snapshot~Feb 2025 – present · 19 months · monthly snapshot

Change History

17 versions recorded

  1. Feb 2025 — Present [monthly]

    Terminated PHASE3

    Status: Completed → Terminated

  2. Sep 2024 — Feb 2025 [monthly]

    Completed PHASE3

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE3

  4. May 2024 — Jul 2024 [monthly]

    Completed PHASE3

  5. Jun 2023 — May 2024 [monthly]

    Completed PHASE3

    Status: Active Not Recruiting → Completed

▶ Show 12 earlier versions

  1. May 2023 — Jun 2023 [monthly]

    Active Not Recruiting PHASE3

  2. Nov 2022 — May 2023 [monthly]

    Active Not Recruiting PHASE3

    Status: Recruiting → Active Not Recruiting

  3. Sep 2022 — Nov 2022 [monthly]

    Recruiting PHASE3

  4. Sep 2021 — Sep 2022 [monthly]

    Recruiting PHASE3

  5. Jan 2021 — Sep 2021 [monthly]

    Recruiting PHASE3

  6. Aug 2020 — Jan 2021 [monthly]

    Recruiting PHASE3

    Status: Suspended → Recruiting

  7. May 2020 — Aug 2020 [monthly]

    Suspended PHASE3

    Status: Recruiting → Suspended

  8. Nov 2019 — May 2020 [monthly]

    Recruiting PHASE3

  9. Jun 2019 — Nov 2019 [monthly]

    Recruiting PHASE3

  10. Nov 2018 — Jun 2019 [monthly]

    Recruiting PHASE3

    Status: Not Yet Recruiting → Recruiting

  11. Oct 2018 — Nov 2018 [monthly]

    Not Yet Recruiting PHASE3

  12. Sep 2018 — Oct 2018 [monthly]

    Not Yet Recruiting PHASE3

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • NYU Langone Health
  • National Institute of Dental and Craniofacial Research (NIDCR)
  • University of Iowa
  • University of Michigan
Data source: University of Michigan

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations