deltatrials
Terminated OBSERVATIONAL NCT03699410

Observational Study on Rectal Cancer to Verify if Response After Chemo-radiotherapy Can be Predicted With a Particular Blood Test. (LiBReCa)

A Proof-of-concept, Prospective, Observational Study to Investigate the Value of Liquid Biopsies to Predict Tumor Response After Neoadjuvant Chemo-radiotherapy in Patients With Locally Advanced Rectal Cancer: the LiBReCa Study

Sponsor: Clinical Trial Unit Ente Ospedaliero Cantonale

Updated 10 times since 2018 Last updated: Oct 5, 2021 Started: Aug 28, 2018 Primary completion: Oct 20, 2020 Completion: Oct 20, 2020
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

failure to identify complete responders since ctDNA disappears after radiotherapy in most patients.

Listed as NCT03699410, this observational or N/A phase trial focuses on Locally Advanced Rectal Cancer and remains terminated or withdrawn. Sponsored by Clinical Trial Unit Ente Ospedaliero Cantonale, it has been updated 10 times since 2018, reflecting substantial change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Nov 2018 – ~Feb 2019 · 3 months · monthly snapshotRecruiting~Feb 2019 – ~Sep 2019 · 7 months · monthly snapshotRecruiting~Sep 2019 – ~Nov 2020 · 14 months · monthly snapshotRecruiting~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshotRecruiting~Jan 2021 – ~Oct 2021 · 9 months · monthly snapshotRecruiting~Oct 2021 – ~Nov 2021 · 31 days · monthly snapshotUnknown Status~Nov 2021 – ~Dec 2021 · 30 days · monthly snapshotTerminated~Dec 2021 – ~Jul 2024 · 31 months · monthly snapshotTerminated~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotTerminated~Sep 2024 – present · 22 months · monthly snapshotTerminated

Change History

10 versions recorded
  1. Sep 2024 — Present [monthly]

    Terminated

  2. Jul 2024 — Sep 2024 [monthly]

    Terminated

  3. Dec 2021 — Jul 2024 [monthly]

    Terminated

  4. Nov 2021 — Dec 2021 [monthly]

    Terminated

    Status: Unknown StatusTerminated

  5. Oct 2021 — Nov 2021 [monthly]

    Unknown Status

    Status: RecruitingUnknown Status

Show 5 earlier versions
  1. Jan 2021 — Oct 2021 [monthly]

    Recruiting

  2. Nov 2020 — Jan 2021 [monthly]

    Recruiting

  3. Sep 2019 — Nov 2020 [monthly]

    Recruiting

  4. Feb 2019 — Sep 2019 [monthly]

    Recruiting

  5. Nov 2018 — Feb 2019 [monthly]

    Recruiting

    First recorded

Aug 2018

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Clinical Trial Unit Ente Ospedaliero Cantonale
  • Dimitri Christoforidis
Data source: Ente Ospedaliero Cantonale, Bellinzona

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations