deltatrials
Completed PHASE4 INTERVENTIONAL 2-arm NCT03753087

Effects of Empagliflozin on Exercise Capacity and Left Ventricular Diastolic Function in Patients With Heart Failure With Preserved Ejection Fraction and Type-2 Diabetes Mellitus

A Phase 4, Single-center, Randomized, Parallel Group Study to Assess Effects of Empagliflozin on Exercise Capacity and Left Ventricular Diastolic Function in Patients With Heart Failure With Preserved Ejection Fraction and Type-2 Diabetes Mellitus

Sponsor: Ministry of Health, Russian Federation

Conditions Diabetes Mellitus, Type 2 Heart Failure, Diastolic
Interventions Empagliflozin Standard care
Updated 9 times since 2018 Last updated: Jan 10, 2022 Started: Jan 16, 2019 Primary completion: Dec 16, 2021 Completion: Jan 10, 2022
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE4 trial investigates Diabetes Mellitus, Type 2 and Heart Failure, Diastolic and is currently completed. Ministry of Health, Russian Federation leads this study, which shows 9 recorded versions since 2019 — indicating limited longitudinal coverage. Heart and vascular conditions benefit from the kind of long-term tracking this trial provides.

Status Flow

~Dec 2018 – ~Feb 2019 · 2 months · monthly snapshotNot Yet Recruiting~Feb 2019 – ~Jan 2021 · 23 months · monthly snapshotRecruiting~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshotRecruiting~Feb 2021 – ~Feb 2022 · 12 months · monthly snapshotUnknown Status~Feb 2022 – ~Jul 2024 · 29 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – ~Feb 2025 · 5 months · monthly snapshotCompleted~Feb 2025 – ~Sep 2025 · 7 months · monthly snapshotCompleted~Sep 2025 – present · 12 months · monthly snapshotCompleted

Change History

9 versions recorded

  1. Sep 2025 — Present [monthly]

    Completed PHASE4

  2. Feb 2025 — Sep 2025 [monthly]

    Completed PHASE4

  3. Sep 2024 — Feb 2025 [monthly]

    Completed PHASE4

  4. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE4

  5. Feb 2022 — Jul 2024 [monthly]

    Completed PHASE4

    Status: Unknown Status → Completed

▶ Show 4 earlier versions

  1. Feb 2021 — Feb 2022 [monthly]

    Unknown Status PHASE4

    Status: Recruiting → Unknown Status

  2. Jan 2021 — Feb 2021 [monthly]

    Recruiting PHASE4

  3. Feb 2019 — Jan 2021 [monthly]

    Recruiting PHASE4

    Status: Not Yet Recruiting → Recruiting

  4. Dec 2018 — Feb 2019 [monthly]

    Not Yet Recruiting PHASE4

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Ministry of Health, Russian Federation
  • National Medical Research Center for Cardiology, Ministry of Health of Russian Federation
Data source: National Medical Research Center for Cardiology, Ministry of Health of Russian Federation

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations