deltatrials
Completed PHASE2 INTERVENTIONAL 2-arm NCT03928158

LCZ696 in Advanced LV Hypertrophy and HFpEF

Sacubitril/Valsartan (LCZ696) in Patients With Advanced Hypertensive Left Ventricular Hypertrophy and Heart Failure With Preserved Ejection Fraction: Clinical, Haemodynamic and Neurohumoral Effects (a Phase 2, Randomized, Single-center, Parallel Group Study)

Sponsor: National Medical Research Center for Cardiology, Ministry of Health of Russian Federation

Updated 12 times since 2019 Last updated: May 21, 2025 Started: May 31, 2019 Primary completion: Jun 30, 2023 Completion: Dec 31, 2023
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE2 trial investigates Essential Hypertension and Heart Failure and is currently completed. National Medical Research Center for Cardiology, Ministry of Health of Russian Federation leads this study, which shows 12 recorded versions since 2019 — indicating substantial longitudinal coverage. Heart and vascular conditions benefit from the kind of long-term tracking this trial provides.

Status Flow

~May 2019 – ~Jul 2019 · 2 months · monthly snapshotNot Yet Recruiting~Jul 2019 – ~Jan 2020 · 6 months · monthly snapshotRecruiting~Jan 2020 – ~Jan 2021 · 12 months · monthly snapshotRecruiting~Jan 2021 – ~Jan 2022 · 12 months · monthly snapshotRecruiting~Jan 2022 – ~Feb 2022 · 31 days · monthly snapshotUnknown Status~Feb 2022 – ~Feb 2024 · 24 months · monthly snapshotRecruiting~Feb 2024 – ~Jul 2024 · 5 months · monthly snapshotUnknown Status~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotUnknown~Sep 2024 – ~Feb 2025 · 5 months · monthly snapshotUnknown~Feb 2025 – ~Jun 2025 · 4 months · monthly snapshotUnknown~Jun 2025 – ~Sep 2025 · 3 months · monthly snapshotCompleted~Sep 2025 – present · 10 months · monthly snapshotCompleted

Change History

12 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE2

  2. Jun 2025 — Sep 2025 [monthly]

    Completed PHASE2

    Status: UnknownCompleted

  3. Feb 2025 — Jun 2025 [monthly]

    Unknown PHASE2

  4. Sep 2024 — Feb 2025 [monthly]

    Unknown PHASE2

  5. Jul 2024 — Sep 2024 [monthly]

    Unknown PHASE2

    Status: Unknown StatusUnknown

Show 7 earlier versions
  1. Feb 2024 — Jul 2024 [monthly]

    Unknown Status PHASE2

    Status: RecruitingUnknown Status

  2. Feb 2022 — Feb 2024 [monthly]

    Recruiting PHASE2

    Status: Unknown StatusRecruiting

  3. Jan 2022 — Feb 2022 [monthly]

    Unknown Status PHASE2

    Status: RecruitingUnknown Status

  4. Jan 2021 — Jan 2022 [monthly]

    Recruiting PHASE2

  5. Jan 2020 — Jan 2021 [monthly]

    Recruiting PHASE2

  6. Jul 2019 — Jan 2020 [monthly]

    Recruiting PHASE2

    Status: Not Yet RecruitingRecruiting

  7. May 2019 — Jul 2019 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • National Medical Research Center for Cardiology, Ministry of Health of Russian Federation
Data source: National Medical Research Center for Cardiology, Ministry of Health of Russian Federation

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations