deltatrials
Completed PHASE1 INTERVENTIONAL 1-arm NCT03810742

Nanoliposomal Irinotecan (Nal-IRI, ONIVYDE®) in Combination With TAS-102 (LONSURF®) in Refractory Solid Tumors

Phase 1 Study of Nanoliposomal Irinotecan (Nal-IRI, ONIVYDE®) in Combination With TAS-102 (LONSURF®) in Refractory Solid Tumors

Sponsor: PharmaEngine

Updated 12 times since 2019 Last updated: Nov 15, 2023 Started: Mar 5, 2019 Primary completion: May 4, 2022 Completion: Oct 25, 2023
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE1 clinical study on Refractory Solid Tumors, this trial is completed. The trial is conducted by PharmaEngine and has accumulated 12 data snapshots since 2019. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Feb 2019 – ~Sep 2019 · 7 months · monthly snapshotNot Yet Recruiting~Sep 2019 – ~Jan 2021 · 16 months · monthly snapshotRecruiting~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshotRecruiting~Feb 2021 – ~Oct 2021 · 8 months · monthly snapshotRecruiting~Oct 2021 – ~Jan 2023 · 15 months · monthly snapshotActive Not Recruiting~Jan 2023 – ~Aug 2023 · 7 months · monthly snapshotActive Not Recruiting~Aug 2023 – ~Dec 2023 · 4 months · monthly snapshotActive Not Recruiting~Dec 2023 – ~Jul 2024 · 7 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotCompleted~Sep 2025 – ~Dec 2025 · 3 months · monthly snapshotCompleted~Dec 2025 – present · 9 months · monthly snapshotCompleted

Change History

12 versions recorded
  1. Dec 2025 — Present [monthly]

    Completed PHASE1

  2. Sep 2025 — Dec 2025 [monthly]

    Completed PHASE1

  3. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE1

  4. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1

  5. Dec 2023 — Jul 2024 [monthly]

    Completed PHASE1

    Status: Active Not RecruitingCompleted

Show 7 earlier versions
  1. Aug 2023 — Dec 2023 [monthly]

    Active Not Recruiting PHASE1

  2. Jan 2023 — Aug 2023 [monthly]

    Active Not Recruiting PHASE1

  3. Oct 2021 — Jan 2023 [monthly]

    Active Not Recruiting PHASE1

    Status: RecruitingActive Not Recruiting

  4. Feb 2021 — Oct 2021 [monthly]

    Recruiting PHASE1

  5. Jan 2021 — Feb 2021 [monthly]

    Recruiting PHASE1

  6. Sep 2019 — Jan 2021 [monthly]

    Recruiting PHASE1

    Status: Not Yet RecruitingRecruiting

  7. Feb 2019 — Sep 2019 [monthly]

    Not Yet Recruiting PHASE1

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • PharmaEngine
Data source: PharmaEngine

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations