deltatrials
Terminated PHASE1/PHASE2 INTERVENTIONAL 3-arm NCT03119064

BrUOG 329 Onivyde & Metronomic Temozolomide in Recurrent Glioblastoma (329)

BrUOG 329: Onivyde (Nanoliposomal Irinotecan) and Metronomic Temozolomide for Patients With Recurrent Glioblastoma: A Phase IB/IIA Brown University Oncology Research Group Study

Sponsor: Brown University

Updated 11 times since 2017 Last updated: Nov 17, 2022 Started: Nov 30, 2017 Primary completion: Apr 10, 2020 Completion: Oct 8, 2021
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

lack of response to study therapy

This PHASE1/PHASE2 trial investigates GBM and Glioblastoma and is currently terminated or withdrawn. Brown University leads this study, which shows 11 recorded versions since 2017 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Jun 2017 – ~Jun 2018 · 12 months · monthly snapshotNot Yet Recruiting~Jun 2018 – ~Sep 2018 · 3 months · monthly snapshotNot Yet Recruiting~Sep 2018 – ~Feb 2019 · 5 months · monthly snapshotRecruiting~Feb 2019 – ~Sep 2020 · 19 months · monthly snapshotRecruiting~Sep 2020 – ~Jan 2021 · 4 months · monthly snapshotCompleted~Jan 2021 – ~Mar 2022 · 14 months · monthly snapshotCompleted~Mar 2022 – ~Sep 2022 · 6 months · monthly snapshotCompleted~Sep 2022 – ~Jan 2023 · 4 months · monthly snapshotTerminated~Jan 2023 – ~Jul 2024 · 18 months · monthly snapshotTerminated~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotTerminated~Sep 2024 – present · 22 months · monthly snapshotTerminated

Change History

11 versions recorded
  1. Sep 2024 — Present [monthly]

    Terminated PHASE1/PHASE2

  2. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE1/PHASE2

    Phase: PHASE1_PHASE2PHASE1/PHASE2

  3. Jan 2023 — Jul 2024 [monthly]

    Terminated PHASE1_PHASE2

  4. Sep 2022 — Jan 2023 [monthly]

    Terminated PHASE1_PHASE2

    Status: CompletedTerminated

  5. Mar 2022 — Sep 2022 [monthly]

    Completed PHASE1_PHASE2

Show 6 earlier versions
  1. Jan 2021 — Mar 2022 [monthly]

    Completed PHASE1_PHASE2

  2. Sep 2020 — Jan 2021 [monthly]

    Completed PHASE1_PHASE2

    Status: RecruitingCompleted

  3. Feb 2019 — Sep 2020 [monthly]

    Recruiting PHASE1_PHASE2

  4. Sep 2018 — Feb 2019 [monthly]

    Recruiting PHASE1_PHASE2

    Status: Not Yet RecruitingRecruiting

  5. Jun 2018 — Sep 2018 [monthly]

    Not Yet Recruiting PHASE1_PHASE2

  6. Jun 2017 — Jun 2018 [monthly]

    Not Yet Recruiting PHASE1_PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Brown University
  • Merrimack Pharmaceuticals
  • Rhode Island Hospital
Data source: Brown University

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations