Methotrexate in the Treatment of Advanced Knee Osteoarthritis With Effusion-synovitis
A Randomized, Double-blind, Placebo-controlled Clinical Trial of Methotrexate (MTX) in the Treatment of Advanced Knee Osteoarthritis With Effusion-synovitis
Sponsor: Beijing Hospital
This NA trial investigates Effusion Synovial and Knee Osteoarthritis and is currently completed. Beijing Hospital leads this study, which shows 11 recorded versions since 2019 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.
Status Flow
Change History
11 versions recorded-
Jun 2025 — Present [monthly]
Completed NA
-
Sep 2024 — Jun 2025 [monthly]
Completed NA
-
Jul 2024 — Sep 2024 [monthly]
Completed NA
-
Mar 2024 — Jul 2024 [monthly]
Completed NA
Status: Active Not Recruiting → Completed
-
Dec 2022 — Mar 2024 [monthly]
Active Not Recruiting NA
Status: Recruiting → Active Not Recruiting
▶ Show 6 earlier versions
-
Sep 2021 — Dec 2022 [monthly]
Recruiting NA
-
Jan 2021 — Sep 2021 [monthly]
Recruiting NA
-
Feb 2020 — Jan 2021 [monthly]
Recruiting NA
Status: Not Yet Recruiting → Recruiting
-
Apr 2019 — Feb 2020 [monthly]
Not Yet Recruiting NA
-
Mar 2019 — Apr 2019 [monthly]
Not Yet Recruiting NA
-
Feb 2019 — Mar 2019 [monthly]
Not Yet Recruiting NA
First recorded
Eligibility Summary
No eligibility information available.
Contact Information
- Beijing Hospital
- Central People's Hospital of Zhanjiang
- Peking Union Medical College Hospital
- Peking University People's Hospital
- Qingyuan People's Hospital
- Shenzhen Third People's Hospital
- The First Affiliated Hospital of Anhui Medical University
- The Second People's Hospital of GuangDong Province
- Third Affiliated Hospital, Sun Yat-Sen University
- Xuanwu Hospital, Beijing
- Zhujiang Hospital
For direct contact, visit the study record on ClinicalTrials.gov .