deltatrials
Terminated EARLY_PHASE1 INTERVENTIONAL 1-arm NCT03890198

A Phase 1 Study of LCAR-C182A Cells in the Treatment of Advanced Gastric Cancer and Pancreatic Ductal Adenocarcinoma

A Phase 1, Open-Label Study Evaluating the Safety, Tolerability and Efficacy of LCAR-C182A, an Anti-Claudin18.2 CAR-T Cell Therapy in Patients With Advanced Gastric Cancer and Pancreatic Ductal Adenocarcinoma

Sponsor: First Affiliated Hospital Xi'an Jiaotong University

Interventions LCAR-C182A cells
Updated 8 times since 2019 Last updated: Jun 30, 2020 Started: Apr 22, 2019 Primary completion: Mar 6, 2020 Completion: Mar 6, 2020
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

the Preliminary data, progress of this study and the adjustment of the pipeline and strategy .

Listed as NCT03890198, this EARLY_PHASE1 trial focuses on Gastric Cancer and Pancreatic Ductal Adenocarcinoma and remains terminated or withdrawn. Sponsored by First Affiliated Hospital Xi'an Jiaotong University, it has been updated 8 times since 2019, reflecting limited change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Apr 2019 – ~Jun 2019 · 2 months · monthly snapshotNot Yet Recruiting~Jun 2019 – ~Dec 2019 · 6 months · monthly snapshotRecruiting~Dec 2019 – ~Aug 2020 · 8 months · monthly snapshotRecruiting~Aug 2020 – ~Jan 2021 · 5 months · monthly snapshotTerminated~Jan 2021 – ~Jul 2024 · 42 months · monthly snapshotTerminated~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotTerminated~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotTerminated~Sep 2025 – present · 10 months · monthly snapshotTerminated

Change History

8 versions recorded
  1. Sep 2025 — Present [monthly]

    Terminated EARLY_PHASE1

  2. Sep 2024 — Sep 2025 [monthly]

    Terminated EARLY_PHASE1

  3. Jul 2024 — Sep 2024 [monthly]

    Terminated EARLY_PHASE1

  4. Jan 2021 — Jul 2024 [monthly]

    Terminated EARLY_PHASE1

  5. Aug 2020 — Jan 2021 [monthly]

    Terminated EARLY_PHASE1

    Status: RecruitingTerminated

Show 3 earlier versions
  1. Dec 2019 — Aug 2020 [monthly]

    Recruiting EARLY_PHASE1

  2. Jun 2019 — Dec 2019 [monthly]

    Recruiting EARLY_PHASE1

    Status: Not Yet RecruitingRecruiting

  3. Apr 2019 — Jun 2019 [monthly]

    Not Yet Recruiting EARLY_PHASE1

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • First Affiliated Hospital Xi'an Jiaotong University
  • Nanjing Legend Biotech Co.
Data source: First Affiliated Hospital Xi'an Jiaotong University

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations