deltatrials
Terminated OBSERVATIONAL NCT03894020

GTSCOPE - To Evaluate the Natural Progression of Dry Age-related Macular Degeneration (AMD)

A Study of Disease Progression in Genetically Defined Subjects With Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD)

Sponsor: Gyroscope Therapeutics Limited

Conditions Dry Age-related Macular Degeneration Geographic Atrophy Macular Atrophy Macular Degeneration Retinal Degeneration Retinal Disease
Updated 27 times since 2019 Last updated: Oct 28, 2024 Started: Jan 8, 2019 Primary completion: Mar 25, 2024 Completion: Mar 25, 2024
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

The study was terminated due to the interim analysis demonstrating lack of treatment efficacy.

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Listed as NCT03894020, this observational or N/A phase trial focuses on Dry Age-related Macular Degeneration and Geographic Atrophy and remains terminated or withdrawn. Sponsored by Gyroscope Therapeutics Limited, it has been updated 27 times since 2019, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Apr 2019 – ~May 2019 · 30 days · monthly snapshot~May 2019 – ~Aug 2019 · 3 months · monthly snapshot~Aug 2019 – ~Sep 2019 · 31 days · monthly snapshot~Sep 2019 – ~Oct 2019 · 30 days · monthly snapshot~Oct 2019 – ~Nov 2019 · 31 days · monthly snapshot~Nov 2019 – ~Dec 2019 · 30 days · monthly snapshot~Dec 2019 – ~Jan 2020 · 31 days · monthly snapshot~Jan 2020 – ~Feb 2020 · 31 days · monthly snapshot~Feb 2020 – ~Mar 2020 · 29 days · monthly snapshot~Mar 2020 – ~Apr 2020 · 31 days · monthly snapshot~Apr 2020 – ~Jul 2020 · 3 months · monthly snapshot~Jul 2020 – ~Aug 2020 · 31 days · monthly snapshot~Aug 2020 – ~Sep 2020 · 31 days · monthly snapshot~Sep 2020 – ~Oct 2020 · 30 days · monthly snapshot~Oct 2020 – ~Nov 2020 · 31 days · monthly snapshot~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshot~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshot~Feb 2021 – ~Mar 2021 · 28 days · monthly snapshot~Mar 2021 – ~Oct 2021 · 7 months · monthly snapshot~Oct 2021 – ~Dec 2021 · 2 months · monthly snapshot~Dec 2021 – ~Jan 2023 · 13 months · monthly snapshot~Jan 2023 – ~Nov 2023 · 10 months · monthly snapshot~Nov 2023 – ~Jul 2024 · 8 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Nov 2024 · 2 months · monthly snapshot~Nov 2024 – ~Sep 2025 · 10 months · monthly snapshot~Sep 2025 – present · 11 months · monthly snapshot

Change History

27 versions recorded

  1. Sep 2025 — Present [monthly]

    Terminated

  2. Nov 2024 — Sep 2025 [monthly]

    Terminated

    Status: Active Not Recruiting → Terminated

  3. Sep 2024 — Nov 2024 [monthly]

    Active Not Recruiting

  4. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting

  5. Nov 2023 — Jul 2024 [monthly]

    Active Not Recruiting

▶ Show 22 earlier versions

  1. Jan 2023 — Nov 2023 [monthly]

    Active Not Recruiting

    Status: Recruiting → Active Not Recruiting

  2. Dec 2021 — Jan 2023 [monthly]

    Recruiting

  3. Oct 2021 — Dec 2021 [monthly]

    Recruiting

  4. Mar 2021 — Oct 2021 [monthly]

    Recruiting

  5. Feb 2021 — Mar 2021 [monthly]

    Recruiting

  6. Jan 2021 — Feb 2021 [monthly]

    Recruiting

  7. Nov 2020 — Jan 2021 [monthly]

    Recruiting

  8. Oct 2020 — Nov 2020 [monthly]

    Recruiting

  9. Sep 2020 — Oct 2020 [monthly]

    Recruiting

  10. Aug 2020 — Sep 2020 [monthly]

    Recruiting

  11. Jul 2020 — Aug 2020 [monthly]

    Recruiting

  12. Apr 2020 — Jul 2020 [monthly]

    Recruiting

  13. Mar 2020 — Apr 2020 [monthly]

    Recruiting

  14. Feb 2020 — Mar 2020 [monthly]

    Recruiting

  15. Jan 2020 — Feb 2020 [monthly]

    Recruiting

  16. Dec 2019 — Jan 2020 [monthly]

    Recruiting

  17. Nov 2019 — Dec 2019 [monthly]

    Recruiting

  18. Oct 2019 — Nov 2019 [monthly]

    Recruiting

  19. Sep 2019 — Oct 2019 [monthly]

    Recruiting

  20. Aug 2019 — Sep 2019 [monthly]

    Recruiting

  21. May 2019 — Aug 2019 [monthly]

    Recruiting

  22. Apr 2019 — May 2019 [monthly]

    Recruiting

    First recorded

Jan 2019

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Gyroscope Therapeutics Limited
  • Novartis Pharmaceuticals
Data source: Gyroscope Therapeutics Limited

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Amsterdam, Netherlands , Augusta, United States , Baltimore, United States , Barcelona, Spain , Bellaire, United States , Bellevue, United States , Beverly Hills, United States , Bordeaux, France , Boston, United States , Burnley, United Kingdom and 57 more locations