deltatrials
Enrolling By Invitation PHASE2 INTERVENTIONAL 1-arm NCT05481827

ORACLE: A Long-term Follow-up Study to Evaluate the Safety of GT005 in Participants With Geographic Atrophy Secondary to Age-related Macular Degeneration Treated in a Gyroscope-sponsored Antecedent Study (ORACLE)

Sponsor: Gyroscope Therapeutics Limited

Interventions GT005
Updated 10 times since 2022 Last updated: Mar 21, 2024 Started: Jul 12, 2022 Primary completion: Jun 2, 2028 Completion: Jun 2, 2028
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT05481827, this PHASE2 trial focuses on Age Related Macular Degeneration (AMD) and remains ongoing. Sponsored by Gyroscope Therapeutics Limited, it has been updated 10 times since 2022, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Sep 2022 – ~Jan 2023 · 4 months · monthly snapshotEnrolling By Invitation~Jan 2023 – ~Sep 2023 · 8 months · monthly snapshotEnrolling By Invitation~Sep 2023 – ~Nov 2023 · 2 months · monthly snapshotEnrolling By Invitation~Nov 2023 – ~Dec 2023 · 30 days · monthly snapshotEnrolling By Invitation~Dec 2023 – ~Jan 2024 · 31 days · monthly snapshotEnrolling By Invitation~Jan 2024 – ~Apr 2024 · 3 months · monthly snapshotEnrolling By Invitation~Apr 2024 – ~Jul 2024 · 3 months · monthly snapshotEnrolling By Invitation~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotEnrolling By Invitation~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotEnrolling By Invitation~Sep 2025 – present · 10 months · monthly snapshotEnrolling By Invitation

Change History

10 versions recorded
  1. Sep 2025 — Present [monthly]

    Enrolling By Invitation PHASE2

  2. Sep 2024 — Sep 2025 [monthly]

    Enrolling By Invitation PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Enrolling By Invitation PHASE2

  4. Apr 2024 — Jul 2024 [monthly]

    Enrolling By Invitation PHASE2

  5. Jan 2024 — Apr 2024 [monthly]

    Enrolling By Invitation PHASE2

Show 5 earlier versions
  1. Dec 2023 — Jan 2024 [monthly]

    Enrolling By Invitation PHASE2

    Phase: NonePHASE2

  2. Nov 2023 — Dec 2023 [monthly]

    Enrolling By Invitation

  3. Sep 2023 — Nov 2023 [monthly]

    Enrolling By Invitation

  4. Jan 2023 — Sep 2023 [monthly]

    Enrolling By Invitation

  5. Sep 2022 — Jan 2023 [monthly]

    Enrolling By Invitation

    First recorded

Jul 2022

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Gyroscope Therapeutics Limited
  • Novartis Pharmaceuticals
Data source: Gyroscope Therapeutics Limited

For direct contact, visit the study record on ClinicalTrials.gov .