deltatrials
Suspended PHASE1 INTERVENTIONAL 1-arm NCT03932253

MEK Inhibitor FCN-159 To Treat Advanced Melanoma With NRAS-aberrant (Ia) and NRAS-mutant (Ib)or NF1-mutant(1b)

A Single-arm Phase Ia/Ib Study to Evaluate the Safety, Tolerability, PK Characteristics and Anti-tumor Activity of FCN-159 in Patients With Advanced Melanoma Harboring NRAS Aberration(Ia)and NRAS/NF1 Mutation(Ib)

Sponsor: Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd.

Conditions Melanoma
Interventions FCN-159
Updated 7 times since 2019 Last updated: Mar 25, 2024 Started: Mar 21, 2019 Primary completion: Apr 30, 2023 Completion: Apr 30, 2024
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Suspended

Sponsor R\&D strategy adjustment

This PHASE1 trial investigates Melanoma and is currently suspended. Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd. leads this study, which shows 7 recorded versions since 2019 — indicating limited longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~May 2019 – ~Jan 2021 · 20 months · monthly snapshotRecruiting~Jan 2021 – ~May 2022 · 16 months · monthly snapshotRecruiting~May 2022 – ~Apr 2023 · 11 months · monthly snapshotRecruiting~Apr 2023 – ~Apr 2024 · 12 months · monthly snapshotUnknown Status~Apr 2024 – ~Jul 2024 · 3 months · monthly snapshotSuspended~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotSuspended~Sep 2024 – present · 22 months · monthly snapshotSuspended

Change History

7 versions recorded
  1. Sep 2024 — Present [monthly]

    Suspended PHASE1

  2. Jul 2024 — Sep 2024 [monthly]

    Suspended PHASE1

  3. Apr 2024 — Jul 2024 [monthly]

    Suspended PHASE1

    Status: Unknown StatusSuspended

  4. Apr 2023 — Apr 2024 [monthly]

    Unknown Status PHASE1

    Status: RecruitingUnknown Status

  5. May 2022 — Apr 2023 [monthly]

    Recruiting PHASE1

Show 2 earlier versions
  1. Jan 2021 — May 2022 [monthly]

    Recruiting PHASE1

  2. May 2019 — Jan 2021 [monthly]

    Recruiting PHASE1

    First recorded

Mar 2019

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd.
Data source: Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd.

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations