deltatrials
Completed PHASE2 INTERVENTIONAL 2-arm NCT05140278

Study to Compare Feasibility of 1-step Injectable Artesunate vs. Conventional 2-step Injectable Artesunate (1STEP-AS)

Convenience and Cost-aspects of a New 1-step Reconstitution Injectable Artesunate Compared to Conventional 2-step Injectable Artesunate for the Treatment of Severe Falciparum Malaria: a Multi-centre Study

Sponsor: National Institute for Medical Research, Tanzania

Conditions Severe Malaria
Updated 10 times since 2022 Last updated: Mar 12, 2024 Started: Jul 18, 2022 Primary completion: Jul 29, 2022 Completion: Aug 11, 2023
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE2 trial investigates Severe Malaria and is currently completed. National Institute for Medical Research, Tanzania leads this study, which shows 10 recorded versions since 2022 — indicating substantial longitudinal coverage. Longitudinal tracking of infectious disease trials helps identify durability of treatment effects.

Status Flow

~Jan 2022 – ~Apr 2022 · 3 months · monthly snapshotNot Yet Recruiting~Apr 2022 – ~May 2022 · 30 days · monthly snapshotNot Yet Recruiting~May 2022 – ~Jul 2022 · 2 months · monthly snapshotNot Yet Recruiting~Jul 2022 – ~Sep 2022 · 2 months · monthly snapshotNot Yet Recruiting~Sep 2022 – ~Nov 2023 · 14 months · monthly snapshotRecruiting~Nov 2023 – ~Apr 2024 · 5 months · monthly snapshotCompleted~Apr 2024 – ~Jul 2024 · 3 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotCompleted~Sep 2025 – present · 10 months · monthly snapshotCompleted

Change History

10 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE2

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE2

  4. Apr 2024 — Jul 2024 [monthly]

    Completed PHASE2

  5. Nov 2023 — Apr 2024 [monthly]

    Completed PHASE2

    Status: RecruitingCompleted

Show 5 earlier versions
  1. Sep 2022 — Nov 2023 [monthly]

    Recruiting PHASE2

    Status: Not Yet RecruitingRecruiting

  2. Jul 2022 — Sep 2022 [monthly]

    Not Yet Recruiting PHASE2

  3. May 2022 — Jul 2022 [monthly]

    Not Yet Recruiting PHASE2

  4. Apr 2022 — May 2022 [monthly]

    Not Yet Recruiting PHASE2

  5. Jan 2022 — Apr 2022 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • National Institute for Medical Research, Tanzania
  • Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd.
  • University of Kinshasa
  • University of Oxford
Data source: University of Oxford

For direct contact, visit the study record on ClinicalTrials.gov .