deltatrials
Completed PHASE2 INTERVENTIONAL 2-arm NCT03935321

NISCI - Nogo Inhibition in Spinal Cord Injury (NISCI)

Antibodies Against Nogo-A to Enhance Plasticity, Regeneration and Functional Recovery After Spinal Cord Injury - A Multicenter International Randomized Double Blind Placebo Controlled Phase II Clinical Proof of Concept Trial

Sponsor: EMSCI.org

Interventions NG-101 Placebos
Updated 16 times since 2019 Last updated: Apr 3, 2023 Started: May 15, 2019 Primary completion: Feb 2, 2023 Completion: Feb 2, 2023
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT03935321, this PHASE2 trial focuses on Spinal Cord Injury, Acute and remains completed. Sponsored by EMSCI.org, it has been updated 16 times since 2019, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Jun 2019 – ~Jul 2019 · 30 days · monthly snapshot~Jul 2019 – ~Aug 2019 · 31 days · monthly snapshot~Aug 2019 – ~Dec 2019 · 4 months · monthly snapshot~Dec 2019 – ~Feb 2020 · 2 months · monthly snapshot~Feb 2020 – ~Apr 2020 · 2 months · monthly snapshot~Apr 2020 – ~Jan 2021 · 9 months · monthly snapshot~Jan 2021 – ~May 2021 · 4 months · monthly snapshot~May 2021 – ~Nov 2021 · 6 months · monthly snapshot~Nov 2021 – ~Sep 2022 · 10 months · monthly snapshot~Sep 2022 – ~Apr 2023 · 7 months · monthly snapshot~Apr 2023 – ~May 2023 · 30 days · monthly snapshot~May 2023 – ~Nov 2023 · 6 months · monthly snapshot~Nov 2023 – ~Jul 2024 · 8 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – present · 10 months · monthly snapshot

Change History

16 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE2

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE2

  4. Nov 2023 — Jul 2024 [monthly]

    Completed PHASE2

  5. May 2023 — Nov 2023 [monthly]

    Completed PHASE2

    Status: Active Not RecruitingCompleted

Show 11 earlier versions
  1. Apr 2023 — May 2023 [monthly]

    Active Not Recruiting PHASE2

  2. Sep 2022 — Apr 2023 [monthly]

    Active Not Recruiting PHASE2

    Status: RecruitingActive Not Recruiting

  3. Nov 2021 — Sep 2022 [monthly]

    Recruiting PHASE2

  4. May 2021 — Nov 2021 [monthly]

    Recruiting PHASE2

  5. Jan 2021 — May 2021 [monthly]

    Recruiting PHASE2

  6. Apr 2020 — Jan 2021 [monthly]

    Recruiting PHASE2

  7. Feb 2020 — Apr 2020 [monthly]

    Recruiting PHASE2

  8. Dec 2019 — Feb 2020 [monthly]

    Recruiting PHASE2

  9. Aug 2019 — Dec 2019 [monthly]

    Recruiting PHASE2

  10. Jul 2019 — Aug 2019 [monthly]

    Recruiting PHASE2

  11. Jun 2019 — Jul 2019 [monthly]

    Recruiting PHASE2

    First recorded

May 2019

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • EMSCI.org
  • Foundation Wings For Life
  • Heidelberg University Hospital Spinal Cord Injury Center
  • Horizon 2020 - European Commission
  • KKS Netzwerk
  • State Secretariat for Education Research and Innovation, Switzerland
  • Swiss Paraplegic Research, Nottwil
  • University of Zurich
Data source: University of Zurich

For direct contact, visit the study record on ClinicalTrials.gov .