deltatrials
Completed PHASE3 INTERVENTIONAL 2-arm NCT03979313

A Study to Evaluate the Safety and Efficacy of MEDI8897 for the Prevention of Medically Attended Lower Respiratory Tract Infection Due to Respiratory Syncytial Virus in Healthy Late Preterm and Term Infants (MELODY) (MELODY)

A Phase 3 Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety and Efficacy of MEDI8897, a Monoclonal Antibody With an Extended Half-life Against Respiratory Syncytial Virus, in Healthy Late Preterm and Term Infants (MELODY)

Sponsor: AstraZeneca

Interventions MEDI8897 Placebo
Updated 33 times since 2019 Last updated: Feb 5, 2024 Started: Jul 23, 2019 Primary completion: Mar 11, 2021 Completion: Mar 21, 2023
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT03979313, this PHASE3 trial focuses on Respiratory Syncytial Virus Infections and remains completed. Sponsored by AstraZeneca, it has been updated 33 times since 2019, reflecting substantial change activity. This study is part of the global effort to build evidence for infectious disease interventions.

Status Flow

~Jul 2019 – ~Sep 2019 · 2 months · monthly snapshot~Sep 2019 – ~Oct 2019 · 30 days · monthly snapshot~Oct 2019 – ~Nov 2019 · 31 days · monthly snapshot~Nov 2019 – ~Dec 2019 · 30 days · monthly snapshot~Dec 2019 – ~Jan 2020 · 31 days · monthly snapshot~Jan 2020 – ~Feb 2020 · 31 days · monthly snapshot~Feb 2020 – ~Mar 2020 · 29 days · monthly snapshot~Mar 2020 – ~Apr 2020 · 31 days · monthly snapshot~Apr 2020 – ~Aug 2020 · 4 months · monthly snapshot~Aug 2020 – ~Sep 2020 · 31 days · monthly snapshot~Sep 2020 – ~Oct 2020 · 30 days · monthly snapshot~Oct 2020 – ~Nov 2020 · 31 days · monthly snapshot~Nov 2020 – ~Dec 2020 · 30 days · monthly snapshot~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshot~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshot~Feb 2021 – ~Mar 2021 · 28 days · monthly snapshot~Mar 2021 – ~Apr 2021 · 31 days · monthly snapshot~Apr 2021 – ~May 2021 · 30 days · monthly snapshot~May 2021 – ~Jun 2021 · 31 days · monthly snapshot~Jun 2021 – ~Sep 2021 · 3 months · monthly snapshot~Sep 2021 – ~Oct 2021 · 30 days · monthly snapshot~Oct 2021 – ~Jan 2022 · 3 months · monthly snapshot~Jan 2022 – ~Apr 2022 · 3 months · monthly snapshot~Apr 2022 – ~Sep 2022 · 5 months · monthly snapshot~Sep 2022 – ~Jul 2023 · 10 months · monthly snapshot~Jul 2023 – ~Mar 2024 · 8 months · monthly snapshot~Mar 2024 – ~Jul 2024 · 4 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – ~Oct 2025 · 30 days · monthly snapshot~Oct 2025 – ~Nov 2025 · 31 days · monthly snapshot~Nov 2025 – ~Feb 2026 · 3 months · monthly snapshot~Feb 2026 – present · 4 months · monthly snapshot

Change History

33 versions recorded
  1. Feb 2026 — Present [monthly]

    Completed PHASE3

  2. Nov 2025 — Feb 2026 [monthly]

    Completed PHASE3

  3. Oct 2025 — Nov 2025 [monthly]

    Completed PHASE3

  4. Sep 2025 — Oct 2025 [monthly]

    Completed PHASE3

  5. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE3

Show 28 earlier versions
  1. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE3

  2. Mar 2024 — Jul 2024 [monthly]

    Completed PHASE3

  3. Jul 2023 — Mar 2024 [monthly]

    Completed PHASE3

    Status: Active Not RecruitingCompleted

  4. Sep 2022 — Jul 2023 [monthly]

    Active Not Recruiting PHASE3

  5. Apr 2022 — Sep 2022 [monthly]

    Active Not Recruiting PHASE3

  6. Jan 2022 — Apr 2022 [monthly]

    Active Not Recruiting PHASE3

    Status: RecruitingActive Not Recruiting

  7. Oct 2021 — Jan 2022 [monthly]

    Recruiting PHASE3

  8. Sep 2021 — Oct 2021 [monthly]

    Recruiting PHASE3

  9. Jun 2021 — Sep 2021 [monthly]

    Recruiting PHASE3

  10. May 2021 — Jun 2021 [monthly]

    Recruiting PHASE3

  11. Apr 2021 — May 2021 [monthly]

    Recruiting PHASE3

  12. Mar 2021 — Apr 2021 [monthly]

    Recruiting PHASE3

  13. Feb 2021 — Mar 2021 [monthly]

    Recruiting PHASE3

  14. Jan 2021 — Feb 2021 [monthly]

    Recruiting PHASE3

  15. Dec 2020 — Jan 2021 [monthly]

    Recruiting PHASE3

  16. Nov 2020 — Dec 2020 [monthly]

    Recruiting PHASE3

  17. Oct 2020 — Nov 2020 [monthly]

    Recruiting PHASE3

  18. Sep 2020 — Oct 2020 [monthly]

    Recruiting PHASE3

  19. Aug 2020 — Sep 2020 [monthly]

    Recruiting PHASE3

  20. Apr 2020 — Aug 2020 [monthly]

    Recruiting PHASE3

  21. Mar 2020 — Apr 2020 [monthly]

    Recruiting PHASE3

  22. Feb 2020 — Mar 2020 [monthly]

    Recruiting PHASE3

  23. Jan 2020 — Feb 2020 [monthly]

    Recruiting PHASE3

  24. Dec 2019 — Jan 2020 [monthly]

    Recruiting PHASE3

  25. Nov 2019 — Dec 2019 [monthly]

    Recruiting PHASE3

  26. Oct 2019 — Nov 2019 [monthly]

    Recruiting PHASE3

  27. Sep 2019 — Oct 2019 [monthly]

    Recruiting PHASE3

    Status: Not Yet RecruitingRecruiting

  28. Jul 2019 — Sep 2019 [monthly]

    Not Yet Recruiting PHASE3

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • AstraZeneca
Data source: AstraZeneca

For direct contact, visit the study record on ClinicalTrials.gov .