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Recruiting OBSERVATIONAL NCT03981575

Estab Biomarkers and Clinical Endpoints in Myotonic Dystrophy Type 1 (END-DM1)

Establishing Biomarkers and Clinical Endpoints in Myotonic Dystrophy Type 1 (END-DM1)

Sponsor: Fondazione Serena Onlus - Centro Clinico NeMO Milano

Updated 23 times since 2019 Last updated: Jun 4, 2025 Started: Jan 1, 2019 Primary completion: Oct 1, 2026 Completion: Dec 1, 2026
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT03981575, this observational or N/A phase trial focuses on DM1 and Myotonic Dystrophy 1 and remains actively recruiting participants. Sponsored by Fondazione Serena Onlus - Centro Clinico NeMO Milano, it has been updated 23 times since 2019, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Jul 2019 – ~Dec 2019 · 5 months · monthly snapshot~Dec 2019 – ~Jan 2020 · 31 days · monthly snapshot~Jan 2020 – ~Apr 2020 · 3 months · monthly snapshot~Apr 2020 – ~Oct 2020 · 6 months · monthly snapshot~Oct 2020 – ~Nov 2020 · 31 days · monthly snapshot~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshot~Jan 2021 – ~Sep 2021 · 8 months · monthly snapshot~Sep 2021 – ~Dec 2021 · 3 months · monthly snapshot~Dec 2021 – ~Jan 2022 · 31 days · monthly snapshot~Jan 2022 – ~Mar 2022 · 59 days · monthly snapshot~Mar 2022 – ~Nov 2022 · 8 months · monthly snapshot~Nov 2022 – ~Mar 2023 · 4 months · monthly snapshot~Mar 2023 – ~May 2023 · 2 months · monthly snapshot~May 2023 – ~Aug 2023 · 3 months · monthly snapshot~Aug 2023 – ~Mar 2024 · 7 months · monthly snapshot~Mar 2024 – ~Jun 2024 · 3 months · monthly snapshot~Jun 2024 – ~Jul 2024 · 30 days · monthly snapshot~Jul 2024 – ~Aug 2024 · 31 days · monthly snapshot~Aug 2024 – ~Sep 2024 · 31 days · monthly snapshot~Sep 2024 – ~Nov 2024 · 2 months · monthly snapshot~Nov 2024 – ~Dec 2024 · 30 days · monthly snapshot~Dec 2024 – ~Jul 2025 · 7 months · monthly snapshot~Jul 2025 – present · 12 months · monthly snapshot

Change History

23 versions recorded
  1. Jul 2025 — Present [monthly]

    Recruiting

  2. Dec 2024 — Jul 2025 [monthly]

    Recruiting

  3. Nov 2024 — Dec 2024 [monthly]

    Recruiting

  4. Sep 2024 — Nov 2024 [monthly]

    Recruiting

  5. Aug 2024 — Sep 2024 [monthly]

    Recruiting

Show 18 earlier versions
  1. Jul 2024 — Aug 2024 [monthly]

    Recruiting

  2. Jun 2024 — Jul 2024 [monthly]

    Recruiting

  3. Mar 2024 — Jun 2024 [monthly]

    Recruiting

  4. Aug 2023 — Mar 2024 [monthly]

    Recruiting

  5. May 2023 — Aug 2023 [monthly]

    Recruiting

  6. Mar 2023 — May 2023 [monthly]

    Recruiting

  7. Nov 2022 — Mar 2023 [monthly]

    Recruiting

  8. Mar 2022 — Nov 2022 [monthly]

    Recruiting

  9. Jan 2022 — Mar 2022 [monthly]

    Recruiting

  10. Dec 2021 — Jan 2022 [monthly]

    Recruiting

  11. Sep 2021 — Dec 2021 [monthly]

    Recruiting

    Status: Enrolling By InvitationRecruiting

  12. Jan 2021 — Sep 2021 [monthly]

    Enrolling By Invitation

  13. Nov 2020 — Jan 2021 [monthly]

    Enrolling By Invitation

  14. Oct 2020 — Nov 2020 [monthly]

    Enrolling By Invitation

    Status: SuspendedEnrolling By Invitation

  15. Apr 2020 — Oct 2020 [monthly]

    Suspended

    Status: RecruitingSuspended

  16. Jan 2020 — Apr 2020 [monthly]

    Recruiting

  17. Dec 2019 — Jan 2020 [monthly]

    Recruiting

  18. Jul 2019 — Dec 2019 [monthly]

    Recruiting

    First recorded

Jan 2019

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Fondazione Serena Onlus - Centro Clinico NeMO Milano
  • Ludwig-Maximilians - University of Munich
  • Ohio State University
  • Radboud University Medical Center
  • Stanford University
  • The Methodist Hospital Research Institute
  • University College London Hospitals
  • University of California, Los Angeles
  • University of Florida
  • University of Iowa
  • University of Rochester
  • Virginia Commonwealth University
Data source: Virginia Commonwealth University

For direct contact, visit the study record on ClinicalTrials.gov .