deltatrials
Recruiting PHASE1 INTERVENTIONAL 1-arm NCT03997370

Evaluation of Dosing Procedures of Chemotherapy Treatment (Carboplatin) With the Contrast Agent Iohexol

Assessment of Carboplatin Clearance Predictors: A PK Study on NCI-Sponsored Clinical Trials or Standard of Care Treatments Using Carboplatin

Sponsor: NRG Oncology

Conditions Malignant Solid Neoplasm
Interventions Biospecimen Collection Carboplatin Iohexol
Updated 32 times since 2019 Last updated: Jan 12, 2026 Started: Jan 15, 2020 Primary completion: Feb 6, 2027 Completion: Feb 6, 2028
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT03997370, this PHASE1 trial focuses on Malignant Solid Neoplasm and remains actively recruiting participants. Sponsored by NRG Oncology, it has been updated 32 times since 2020, reflecting substantial change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Jul 2019 – ~Aug 2019 · 31 days · monthly snapshot~Aug 2019 – ~Nov 2019 · 3 months · monthly snapshot~Nov 2019 – ~Dec 2019 · 30 days · monthly snapshot~Dec 2019 – ~Jan 2020 · 31 days · monthly snapshot~Jan 2020 – ~Feb 2020 · 31 days · monthly snapshot~Feb 2020 – ~Mar 2020 · 29 days · monthly snapshot~Mar 2020 – ~Apr 2020 · 31 days · monthly snapshot~Apr 2020 – ~May 2020 · 30 days · monthly snapshot~May 2020 – ~Jun 2020 · 31 days · monthly snapshot~Jun 2020 – ~Jul 2020 · 30 days · monthly snapshot~Jul 2020 – ~Aug 2020 · 31 days · monthly snapshot~Aug 2020 – ~Sep 2020 · 31 days · monthly snapshot~Sep 2020 – ~Jan 2021 · 4 months · monthly snapshot~Jan 2021 – ~Sep 2021 · 8 months · monthly snapshot~Sep 2021 – ~Dec 2021 · 3 months · monthly snapshot~Dec 2021 – ~Feb 2022 · 2 months · monthly snapshot~Feb 2022 – ~Mar 2022 · 28 days · monthly snapshot~Mar 2022 – ~May 2022 · 2 months · monthly snapshot~May 2022 – ~Jul 2022 · 2 months · monthly snapshot~Jul 2022 – ~Sep 2022 · 2 months · monthly snapshot~Sep 2022 – ~Mar 2023 · 6 months · monthly snapshot~Mar 2023 – ~Oct 2023 · 7 months · monthly snapshot~Oct 2023 – ~Dec 2023 · 2 months · monthly snapshot~Dec 2023 – ~Jun 2024 · 6 months · monthly snapshot~Jun 2024 – ~Jul 2024 · 30 days · monthly snapshot~Jul 2024 – ~Aug 2024 · 31 days · monthly snapshot~Aug 2024 – ~Sep 2024 · 31 days · monthly snapshot~Sep 2024 – ~Jun 2025 · 9 months · monthly snapshot~Jun 2025 – ~Sep 2025 · 3 months · monthly snapshot~Sep 2025 – ~Nov 2025 · 2 months · monthly snapshot~Nov 2025 – ~Feb 2026 · 3 months · monthly snapshot~Feb 2026 – present · 6 months · monthly snapshot

Change History

32 versions recorded

  1. Feb 2026 — Present [monthly]

    Recruiting PHASE1

  2. Nov 2025 — Feb 2026 [monthly]

    Recruiting PHASE1

  3. Sep 2025 — Nov 2025 [monthly]

    Recruiting PHASE1

  4. Jun 2025 — Sep 2025 [monthly]

    Recruiting PHASE1

  5. Sep 2024 — Jun 2025 [monthly]

    Recruiting PHASE1

▶ Show 27 earlier versions

  1. Aug 2024 — Sep 2024 [monthly]

    Recruiting PHASE1

  2. Jul 2024 — Aug 2024 [monthly]

    Recruiting PHASE1

  3. Jun 2024 — Jul 2024 [monthly]

    Recruiting PHASE1

  4. Dec 2023 — Jun 2024 [monthly]

    Recruiting PHASE1

  5. Oct 2023 — Dec 2023 [monthly]

    Recruiting PHASE1

  6. Mar 2023 — Oct 2023 [monthly]

    Recruiting PHASE1

  7. Sep 2022 — Mar 2023 [monthly]

    Recruiting PHASE1

  8. Jul 2022 — Sep 2022 [monthly]

    Recruiting PHASE1

  9. May 2022 — Jul 2022 [monthly]

    Recruiting PHASE1

  10. Mar 2022 — May 2022 [monthly]

    Recruiting PHASE1

  11. Feb 2022 — Mar 2022 [monthly]

    Recruiting PHASE1

  12. Dec 2021 — Feb 2022 [monthly]

    Recruiting PHASE1

    Phase: NA → PHASE1

  13. Sep 2021 — Dec 2021 [monthly]

    Recruiting NA

  14. Jan 2021 — Sep 2021 [monthly]

    Recruiting NA

  15. Sep 2020 — Jan 2021 [monthly]

    Recruiting NA

  16. Aug 2020 — Sep 2020 [monthly]

    Recruiting NA

  17. Jul 2020 — Aug 2020 [monthly]

    Recruiting NA

  18. Jun 2020 — Jul 2020 [monthly]

    Recruiting NA

  19. May 2020 — Jun 2020 [monthly]

    Recruiting NA

  20. Apr 2020 — May 2020 [monthly]

    Recruiting NA

  21. Mar 2020 — Apr 2020 [monthly]

    Recruiting NA

  22. Feb 2020 — Mar 2020 [monthly]

    Recruiting NA

  23. Jan 2020 — Feb 2020 [monthly]

    Recruiting NA

  24. Dec 2019 — Jan 2020 [monthly]

    Recruiting NA

    Status: Not Yet Recruiting → Recruiting

  25. Nov 2019 — Dec 2019 [monthly]

    Not Yet Recruiting NA

  26. Aug 2019 — Nov 2019 [monthly]

    Not Yet Recruiting NA

  27. Jul 2019 — Aug 2019 [monthly]

    Not Yet Recruiting NA

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • NRG Oncology
  • National Cancer Institute (NCI)
Data source: NRG Oncology

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Alton, United States , Anaconda, United States , Ankeny, United States , Atlanta, United States , Aurora, United States , Baker City, United States , Ballwin, United States , Baltimore, United States , Basking Ridge, United States , Baton Rouge, United States and 127 more locations