deltatrials
Unknown PHASE3 INTERVENTIONAL 2-arm NCT04007874

Oral Contraceptive Pill Compared With Vitamin E in Women With Migraine (WHATT)

Open-label Randomized Controlled Trial for the Effects of Continuous Ethinylestradiol/Levonorgestrel (30/150 μg/Day) Compared With Vitamin E (400 IU/Day) in the Treatment of Menstrually-related Migraine and Migraine During Perimenopause

Sponsor: Erasmus Medical Center

Updated 11 times since 2019 Last updated: Dec 7, 2023 Started: Sep 10, 2019 Primary completion: Dec 31, 2024 Completion: Dec 31, 2024
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE3 trial investigates Migraine and Migraine;Menstrual and is currently ongoing. Erasmus Medical Center leads this study, which shows 11 recorded versions since 2019 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Aug 2019 – ~Sep 2019 · 31 days · monthly snapshotNot Yet Recruiting~Sep 2019 – ~Nov 2019 · 2 months · monthly snapshotNot Yet Recruiting~Nov 2019 – ~Jan 2021 · 14 months · monthly snapshotRecruiting~Jan 2021 – ~Mar 2021 · 59 days · monthly snapshotRecruiting~Mar 2021 – ~Oct 2021 · 7 months · monthly snapshotRecruiting~Oct 2021 – ~May 2022 · 7 months · monthly snapshotRecruiting~May 2022 – ~Jan 2024 · 20 months · monthly snapshotRecruiting~Jan 2024 – ~Jul 2024 · 6 months · monthly snapshotRecruiting~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotRecruiting~Sep 2024 – ~Feb 2026 · 17 months · monthly snapshotRecruiting~Feb 2026 – present · 5 months · monthly snapshotUnknown

Change History

11 versions recorded
  1. Feb 2026 — Present [monthly]

    Unknown PHASE3

    Status: RecruitingUnknown

  2. Sep 2024 — Feb 2026 [monthly]

    Recruiting PHASE3

  3. Jul 2024 — Sep 2024 [monthly]

    Recruiting PHASE3

  4. Jan 2024 — Jul 2024 [monthly]

    Recruiting PHASE3

  5. May 2022 — Jan 2024 [monthly]

    Recruiting PHASE3

Show 6 earlier versions
  1. Oct 2021 — May 2022 [monthly]

    Recruiting PHASE3

  2. Mar 2021 — Oct 2021 [monthly]

    Recruiting PHASE3

  3. Jan 2021 — Mar 2021 [monthly]

    Recruiting PHASE3

  4. Nov 2019 — Jan 2021 [monthly]

    Recruiting PHASE3

    Status: Not Yet RecruitingRecruiting

  5. Sep 2019 — Nov 2019 [monthly]

    Not Yet Recruiting PHASE3

  6. Aug 2019 — Sep 2019 [monthly]

    Not Yet Recruiting PHASE3

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Erasmus Medical Center
  • Leiden University Medical Center
  • Netherlands Brain Foundation
  • ZonMw: The Netherlands Organisation for Health Research and Development
Data source: Leiden University Medical Center

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations