deltatrials
Unknown PHASE1 INTERVENTIONAL 2-arm NCT04020016

Nalbuphine ER Effects of Liver Disease on Pharmacokinetics and Itch

A Study of Nalbuphine Extended-release (NAL ER) Oral Tablets in Subjects With Impaired Hepatic Function Compared to Healthy Subjects and Exploratory Effect on Itch

Sponsor: Syneos Health

Updated 11 times since 2019 Last updated: Oct 5, 2020 Started: Oct 24, 2018 Primary completion: Nov 30, 2020 Completion: Dec 31, 2020
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE1 clinical study on Hepatic Impairment and Nalbuphine, this trial is ongoing. The trial is conducted by Syneos Health and has accumulated 11 data snapshots since 2018. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

~Aug 2019 – ~Sep 2019 · 31 days · monthly snapshotSuspended~Sep 2019 – ~Mar 2020 · 6 months · monthly snapshotSuspended~Mar 2020 – ~Jul 2020 · 4 months · monthly snapshotRecruiting~Jul 2020 – ~Sep 2020 · 2 months · monthly snapshotRecruiting~Sep 2020 – ~Oct 2020 · 30 days · monthly snapshotRecruiting~Oct 2020 – ~Nov 2020 · 31 days · monthly snapshotActive Not Recruiting~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshotActive Not Recruiting~Jan 2021 – ~Nov 2022 · 22 months · monthly snapshotActive Not Recruiting~Nov 2022 – ~Jul 2024 · 20 months · monthly snapshotUnknown Status~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotUnknown~Sep 2024 – present · 22 months · monthly snapshotUnknown

Change History

11 versions recorded
  1. Sep 2024 — Present [monthly]

    Unknown PHASE1

  2. Jul 2024 — Sep 2024 [monthly]

    Unknown PHASE1

    Status: Unknown StatusUnknown

  3. Nov 2022 — Jul 2024 [monthly]

    Unknown Status PHASE1

    Status: Active Not RecruitingUnknown Status

  4. Jan 2021 — Nov 2022 [monthly]

    Active Not Recruiting PHASE1

  5. Nov 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE1

Show 6 earlier versions
  1. Oct 2020 — Nov 2020 [monthly]

    Active Not Recruiting PHASE1

    Status: RecruitingActive Not Recruiting

  2. Sep 2020 — Oct 2020 [monthly]

    Recruiting PHASE1

  3. Jul 2020 — Sep 2020 [monthly]

    Recruiting PHASE1

  4. Mar 2020 — Jul 2020 [monthly]

    Recruiting PHASE1

    Status: SuspendedRecruiting

  5. Sep 2019 — Mar 2020 [monthly]

    Suspended PHASE1

  6. Aug 2019 — Sep 2019 [monthly]

    Suspended PHASE1

    First recorded

Oct 2018

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Syneos Health
  • Trevi Therapeutics
Data source: Trevi Therapeutics

For direct contact, visit the study record on ClinicalTrials.gov .