deltatrials
Terminated PHASE4 INTERVENTIONAL 2-arm NCT04031885

A Study of Abemaciclib (LY2835219) in Combination With Fulvestrant Compared to Chemotherapy in Women With HR Positive, HER2 Negative Metastatic Breast Cancer

A Multicenter, Open-Label, Randomized-Controlled Study of Abemaciclib, a CDK4 and 6 Inhibitor, in Combination With Fulvestrant Compared to Chemotherapy in Women With HR Positive, HER2 Negative Metastatic Breast Cancer With Visceral Metastases

Sponsor: Eli Lilly and Company

Updated 19 times since 2019 Last updated: Jul 29, 2021 Started: Aug 14, 2019 Primary completion: Aug 11, 2020 Completion: Aug 11, 2020
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Business decision based on the inability to enroll subjects into the trial

Listed as NCT04031885, this PHASE4 trial focuses on Metastatic Breast Cancer and remains terminated or withdrawn. Sponsored by Eli Lilly and Company, it has been updated 19 times since 2019, reflecting substantial change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Aug 2019 – ~Sep 2019 · 31 days · monthly snapshot~Sep 2019 – ~Oct 2019 · 30 days · monthly snapshot~Oct 2019 – ~Nov 2019 · 31 days · monthly snapshot~Nov 2019 – ~Dec 2019 · 30 days · monthly snapshot~Dec 2019 – ~Jan 2020 · 31 days · monthly snapshot~Jan 2020 – ~Feb 2020 · 31 days · monthly snapshot~Feb 2020 – ~Mar 2020 · 29 days · monthly snapshot~Mar 2020 – ~Apr 2020 · 31 days · monthly snapshot~Apr 2020 – ~May 2020 · 30 days · monthly snapshot~May 2020 – ~Nov 2020 · 6 months · monthly snapshot~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshot~Jan 2021 – ~Sep 2021 · 8 months · monthly snapshot~Sep 2021 – ~Dec 2021 · 3 months · monthly snapshot~Dec 2021 – ~Dec 2022 · 12 months · monthly snapshot~Dec 2022 – ~Jan 2023 · 31 days · monthly snapshot~Jan 2023 – ~Jul 2024 · 18 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – present · 10 months · monthly snapshot

Change History

19 versions recorded
  1. Sep 2025 — Present [monthly]

    Terminated PHASE4

  2. Sep 2024 — Sep 2025 [monthly]

    Terminated PHASE4

  3. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE4

  4. Jan 2023 — Jul 2024 [monthly]

    Terminated PHASE4

  5. Dec 2022 — Jan 2023 [monthly]

    Terminated PHASE4

Show 14 earlier versions
  1. Dec 2021 — Dec 2022 [monthly]

    Terminated PHASE4

  2. Sep 2021 — Dec 2021 [monthly]

    Terminated PHASE4

  3. Jan 2021 — Sep 2021 [monthly]

    Terminated PHASE4

  4. Nov 2020 — Jan 2021 [monthly]

    Terminated PHASE4

    Status: SuspendedTerminated

  5. May 2020 — Nov 2020 [monthly]

    Suspended PHASE4

    Status: RecruitingSuspended

  6. Apr 2020 — May 2020 [monthly]

    Recruiting PHASE4

  7. Mar 2020 — Apr 2020 [monthly]

    Recruiting PHASE4

  8. Feb 2020 — Mar 2020 [monthly]

    Recruiting PHASE4

  9. Jan 2020 — Feb 2020 [monthly]

    Recruiting PHASE4

  10. Dec 2019 — Jan 2020 [monthly]

    Recruiting PHASE4

  11. Nov 2019 — Dec 2019 [monthly]

    Recruiting PHASE4

  12. Oct 2019 — Nov 2019 [monthly]

    Recruiting PHASE4

    Status: Not Yet RecruitingRecruiting

  13. Sep 2019 — Oct 2019 [monthly]

    Not Yet Recruiting PHASE4

  14. Aug 2019 — Sep 2019 [monthly]

    Not Yet Recruiting PHASE4

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Eli Lilly and Company
Data source: Eli Lilly and Company

For direct contact, visit the study record on ClinicalTrials.gov .