deltatrials
Completed PHASE1 INTERVENTIONAL 9-arm NCT01655225

A Study of LY3023414 in Participants With Advanced Cancer

A Phase 1 First-in-Human Dose Study of LY3023414 in Patients With Advanced Cancer

Sponsor: Eli Lilly and Company

Conditions Advanced Cancer Malignant Mesothelioma Metastatic Breast Cancer Metastatic Cancer Non-Hodgkin's Lymphoma Non-small Cell Lung Cancer
Interventions Abemaciclib Cisplatin Fulvestrant LY3023414 Letrozole Midazolam Pemetrexed
Updated 26 times since 2017 Last updated: Apr 7, 2022 Started: Jul 31, 2012 Primary completion: Apr 4, 2019 Completion: Feb 2, 2022
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT01655225, this PHASE1 trial focuses on Advanced Cancer and Malignant Mesothelioma and remains completed. Sponsored by Eli Lilly and Company, it has been updated 26 times since 2012, reflecting substantial change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Apr 2017 · 59 days · monthly snapshot~Apr 2017 – ~Jul 2017 · 3 months · monthly snapshot~Jul 2017 – ~Aug 2017 · 31 days · monthly snapshot~Aug 2017 – ~Oct 2017 · 2 months · monthly snapshot~Oct 2017 – ~Jun 2018 · 8 months · monthly snapshot~Jun 2018 – ~Oct 2018 · 4 months · monthly snapshot~Oct 2018 – ~Nov 2018 · 31 days · monthly snapshot~Nov 2018 – ~Dec 2018 · 30 days · monthly snapshot~Dec 2018 – ~Jan 2019 · 31 days · monthly snapshot~Jan 2019 – ~Feb 2019 · 31 days · monthly snapshot~Feb 2019 – ~Mar 2019 · 28 days · monthly snapshot~Mar 2019 – ~Apr 2019 · 31 days · monthly snapshot~Apr 2019 – ~May 2019 · 30 days · monthly snapshot~May 2019 – ~Jun 2019 · 31 days · monthly snapshot~Jun 2019 – ~Jul 2019 · 30 days · monthly snapshot~Jul 2019 – ~Mar 2020 · 8 months · monthly snapshot~Mar 2020 – ~Jan 2021 · 10 months · monthly snapshot~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshot~Feb 2021 – ~Mar 2021 · 28 days · monthly snapshot~Mar 2021 – ~Sep 2021 · 6 months · monthly snapshot~Sep 2021 – ~Feb 2022 · 5 months · monthly snapshot~Feb 2022 – ~May 2022 · 3 months · monthly snapshot~May 2022 – ~Jul 2024 · 26 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – present · 24 months · monthly snapshot

Change History

26 versions recorded

  1. Sep 2024 — Present [monthly]

    Completed PHASE1

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1

  3. May 2022 — Jul 2024 [monthly]

    Completed PHASE1

    Status: Active Not Recruiting → Completed

  4. Feb 2022 — May 2022 [monthly]

    Active Not Recruiting PHASE1

  5. Sep 2021 — Feb 2022 [monthly]

    Active Not Recruiting PHASE1

▶ Show 21 earlier versions

  1. Mar 2021 — Sep 2021 [monthly]

    Active Not Recruiting PHASE1

  2. Feb 2021 — Mar 2021 [monthly]

    Active Not Recruiting PHASE1

  3. Jan 2021 — Feb 2021 [monthly]

    Active Not Recruiting PHASE1

  4. Mar 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE1

  5. Jul 2019 — Mar 2020 [monthly]

    Active Not Recruiting PHASE1

    Status: Recruiting → Active Not Recruiting

  6. Jun 2019 — Jul 2019 [monthly]

    Recruiting PHASE1

  7. May 2019 — Jun 2019 [monthly]

    Recruiting PHASE1

  8. Apr 2019 — May 2019 [monthly]

    Recruiting PHASE1

  9. Mar 2019 — Apr 2019 [monthly]

    Recruiting PHASE1

  10. Feb 2019 — Mar 2019 [monthly]

    Recruiting PHASE1

  11. Jan 2019 — Feb 2019 [monthly]

    Recruiting PHASE1

  12. Dec 2018 — Jan 2019 [monthly]

    Recruiting PHASE1

  13. Nov 2018 — Dec 2018 [monthly]

    Recruiting PHASE1

  14. Oct 2018 — Nov 2018 [monthly]

    Recruiting PHASE1

  15. Jun 2018 — Oct 2018 [monthly]

    Recruiting PHASE1

  16. Oct 2017 — Jun 2018 [monthly]

    Recruiting PHASE1

  17. Aug 2017 — Oct 2017 [monthly]

    Recruiting PHASE1

  18. Jul 2017 — Aug 2017 [monthly]

    Recruiting PHASE1

  19. Apr 2017 — Jul 2017 [monthly]

    Recruiting PHASE1

  20. Feb 2017 — Apr 2017 [monthly]

    Recruiting PHASE1

  21. Jan 2017 — Feb 2017 [monthly]

    Recruiting PHASE1

    First recorded

Jul 2012

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Eli Lilly and Company
Data source: Eli Lilly and Company

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations