deltatrials
Completed PHASE1/PHASE2 INTERVENTIONAL 8-arm NCT04048135

A Multiple Ascending Dose Study of Pegozafermin in Participants With Biopsy Confirmed Nonalcoholic Steatohepatitis (NASH) or Nonalcoholic Fatty Liver Disease (NAFLD) and at High Risk of NASH

A Randomized, Double-Blind, Placebo-Controlled, Multiple Ascending Dose Study to Evaluate the Safety, Tolerability and Pharmacokinetic Properties of BIO89-100 Administered Subcutaneously in Subjects With Nonalcoholic Steatohepatitis (NASH) or With Nonalcoholic Fatty Liver Disease (NAFLD) and at High Risk of NASH

Sponsor: 89bio, Inc.

Conditions NASH
Updated 11 times since 2019 Last updated: Mar 4, 2024 Started: Jul 29, 2019 Primary completion: Aug 28, 2020 Completion: Jan 19, 2022
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE1/PHASE2 clinical study on NASH, this trial is completed. The trial is conducted by 89bio, Inc. and has accumulated 11 data snapshots since 2019. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

~Sep 2019 – ~Apr 2020 · 7 months · monthly snapshotRecruiting~Apr 2020 – ~May 2020 · 30 days · monthly snapshotRecruiting~May 2020 – ~Sep 2020 · 4 months · monthly snapshotActive Not Recruiting~Sep 2020 – ~Jan 2021 · 4 months · monthly snapshotActive Not Recruiting~Jan 2021 – ~Sep 2021 · 8 months · monthly snapshotActive Not Recruiting~Sep 2021 – ~Dec 2022 · 15 months · monthly snapshotActive Not Recruiting~Dec 2022 – ~Feb 2023 · 2 months · monthly snapshotCompleted~Feb 2023 – ~May 2024 · 15 months · monthly snapshotCompleted~May 2024 – ~Jul 2024 · 2 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – present · 24 months · monthly snapshotCompleted

Change History

11 versions recorded
  1. Sep 2024 — Present [monthly]

    Completed PHASE1/PHASE2

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1/PHASE2

    Phase: PHASE1_PHASE2PHASE1/PHASE2

  3. May 2024 — Jul 2024 [monthly]

    Completed PHASE1_PHASE2

  4. Feb 2023 — May 2024 [monthly]

    Completed PHASE1_PHASE2

  5. Dec 2022 — Feb 2023 [monthly]

    Completed PHASE1_PHASE2

    Status: Active Not RecruitingCompleted

Show 6 earlier versions
  1. Sep 2021 — Dec 2022 [monthly]

    Active Not Recruiting PHASE1_PHASE2

  2. Jan 2021 — Sep 2021 [monthly]

    Active Not Recruiting PHASE1_PHASE2

  3. Sep 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE1_PHASE2

  4. May 2020 — Sep 2020 [monthly]

    Active Not Recruiting PHASE1_PHASE2

    Status: RecruitingActive Not Recruiting

  5. Apr 2020 — May 2020 [monthly]

    Recruiting PHASE1_PHASE2

  6. Sep 2019 — Apr 2020 [monthly]

    Recruiting PHASE1_PHASE2

    First recorded

Jul 2019

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • 89bio, Inc.
  • ProSciento, Inc.
Data source: 89bio, Inc.

For direct contact, visit the study record on ClinicalTrials.gov .