deltatrials
Completed PHASE2 INTERVENTIONAL 6-arm NCT04929483

Study Evaluating the Safety, Efficacy and Tolerability of BIO89-100 in Subjects With Biopsy-confirmed Nonalcoholic Steatohepatitis (NASH) (ENLIVEN)

A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy, Safety and Tolerability of BIO89-100 in Subjects With Biopsy-Confirmed Nonalcoholic Steatohepatitis (NASH)

Sponsor: 89bio, Inc.

Updated 14 times since 2021 Last updated: Dec 16, 2025 Started: Jun 4, 2021 Primary completion: Feb 14, 2023 Completion: Oct 8, 2024
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE2 trial investigates NASH - Nonalcoholic Steatohepatitis and is currently completed. 89bio, Inc. leads this study, which shows 14 recorded versions since 2021 — indicating substantial longitudinal coverage. Longitudinal tracking of infectious disease trials helps identify durability of treatment effects.

Status Flow

~Sep 2021 – ~Dec 2021 · 3 months · monthly snapshot~Dec 2021 – ~Feb 2022 · 2 months · monthly snapshot~Feb 2022 – ~Sep 2022 · 7 months · monthly snapshot~Sep 2022 – ~Aug 2023 · 11 months · monthly snapshot~Aug 2023 – ~Feb 2024 · 6 months · monthly snapshot~Feb 2024 – ~Mar 2024 · 29 days · monthly snapshot~Mar 2024 – ~Jul 2024 · 4 months · monthly snapshot~Jul 2024 – ~Aug 2024 · 31 days · monthly snapshot~Aug 2024 – ~Sep 2024 · 31 days · monthly snapshot~Sep 2024 – ~Oct 2024 · 30 days · monthly snapshot~Oct 2024 – ~Mar 2025 · 5 months · monthly snapshot~Mar 2025 – ~Sep 2025 · 6 months · monthly snapshot~Sep 2025 – ~Feb 2026 · 5 months · monthly snapshot~Feb 2026 – present · 7 months · monthly snapshot

Change History

14 versions recorded
  1. Feb 2026 — Present [monthly]

    Completed PHASE2

  2. Sep 2025 — Feb 2026 [monthly]

    Completed PHASE2

  3. Mar 2025 — Sep 2025 [monthly]

    Completed PHASE2

    Status: Active Not RecruitingCompleted

  4. Oct 2024 — Mar 2025 [monthly]

    Active Not Recruiting PHASE2

  5. Sep 2024 — Oct 2024 [monthly]

    Active Not Recruiting PHASE2

Show 9 earlier versions
  1. Aug 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE2

  2. Jul 2024 — Aug 2024 [monthly]

    Active Not Recruiting PHASE2

  3. Mar 2024 — Jul 2024 [monthly]

    Active Not Recruiting PHASE2

  4. Feb 2024 — Mar 2024 [monthly]

    Active Not Recruiting PHASE2

  5. Aug 2023 — Feb 2024 [monthly]

    Active Not Recruiting PHASE2

  6. Sep 2022 — Aug 2023 [monthly]

    Active Not Recruiting PHASE2

    Status: RecruitingActive Not Recruiting

  7. Feb 2022 — Sep 2022 [monthly]

    Recruiting PHASE2

  8. Dec 2021 — Feb 2022 [monthly]

    Recruiting PHASE2

  9. Sep 2021 — Dec 2021 [monthly]

    Recruiting PHASE2

    First recorded

Jun 2021

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • 89bio, Inc.
Data source: 89bio, Inc.

For direct contact, visit the study record on ClinicalTrials.gov .