deltatrials
Terminated PHASE2 INTERVENTIONAL 1-arm NCT04069260

A Phase 2 Study of ELX-02 in Patients With Nephropathic Cystinosis

A Phase 2, Single Center, Open-Label, Multiple Dose Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Daily Subcutaneously Administered ELX-02 in Patients With Nephropathic Cystinosis Bearing One or More CTNS Gene (Cystinosin) Nonsense Mutations

Sponsor: Eloxx Pharmaceuticals, Inc.

Interventions ELX-02
Updated 10 times since 2019 Last updated: May 22, 2020 Started: Aug 2, 2019 Primary completion: Dec 17, 2019 Completion: Dec 17, 2019
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Due to study design limitations, this study has been discontinued and will not proceed with the 2nd cohort as contemplated in the original protocol.

Other terminated trials from Eloxx Pharmaceuticals, Inc.

More terminations from Eloxx Pharmaceuticals, Inc.

This PHASE2 trial investigates Cystinosis and Genetic Disease and is currently terminated or withdrawn. Eloxx Pharmaceuticals, Inc. leads this study, which shows 10 recorded versions since 2019 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Sep 2019 – ~Nov 2019 · 2 months · monthly snapshotRecruiting~Nov 2019 – ~Jan 2020 · 2 months · monthly snapshotRecruiting~Jan 2020 – ~Jun 2020 · 5 months · monthly snapshotRecruiting~Jun 2020 – ~Nov 2020 · 5 months · monthly snapshotTerminated~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshotTerminated~Jan 2021 – ~Dec 2021 · 11 months · monthly snapshotTerminated~Dec 2021 – ~Jul 2024 · 31 months · monthly snapshotTerminated~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotTerminated~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotTerminated~Sep 2025 – present · 10 months · monthly snapshotTerminated

Change History

10 versions recorded
  1. Sep 2025 — Present [monthly]

    Terminated PHASE2

  2. Sep 2024 — Sep 2025 [monthly]

    Terminated PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE2

  4. Dec 2021 — Jul 2024 [monthly]

    Terminated PHASE2

  5. Jan 2021 — Dec 2021 [monthly]

    Terminated PHASE2

Show 5 earlier versions
  1. Nov 2020 — Jan 2021 [monthly]

    Terminated PHASE2

  2. Jun 2020 — Nov 2020 [monthly]

    Terminated PHASE2

    Status: RecruitingTerminated

  3. Jan 2020 — Jun 2020 [monthly]

    Recruiting PHASE2

  4. Nov 2019 — Jan 2020 [monthly]

    Recruiting PHASE2

  5. Sep 2019 — Nov 2019 [monthly]

    Recruiting PHASE2

    First recorded

Aug 2019

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Eloxx Pharmaceuticals, Inc.
Data source: Eloxx Pharmaceuticals, Inc.

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations