deltatrials
Active Not Recruiting PHASE3 INTERVENTIONAL 3-arm NCT04102020

A Study of Oral Venetoclax Tablets and Oral Azacitidine as Maintenance Therapy in Adult Participants With Acute Myeloid Leukemia in First Remission After Conventional Chemotherapy (VIALE-M)

Multicenter, Phase 3 Study of Venetoclax and Azacitidine as Maintenance Therapy for Patients With Acute Myeloid Leukemia in First Remission After Conventional Chemotherapy

Sponsor: AbbVie

Updated 43 times since 2019 Last updated: Aug 19, 2025 Started: Mar 26, 2020 Primary completion: Sep 29, 2022 Completion: Jun 30, 2026
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE3 trial investigates Acute Myeloid Leukemia (AML) and is currently ongoing. AbbVie leads this study, which shows 43 recorded versions since 2020 — indicating substantial longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Oct 2019 – ~Dec 2019 · 2 months · monthly snapshot~Dec 2019 – ~Feb 2020 · 2 months · monthly snapshot~Feb 2020 – ~Mar 2020 · 29 days · monthly snapshot~Mar 2020 – ~Apr 2020 · 31 days · monthly snapshot~Apr 2020 – ~Jun 2020 · 2 months · monthly snapshot~Jun 2020 – ~Jul 2020 · 30 days · monthly snapshot~Jul 2020 – ~Aug 2020 · 31 days · monthly snapshot~Aug 2020 – ~Sep 2020 · 31 days · monthly snapshot~Sep 2020 – ~Oct 2020 · 30 days · monthly snapshot~Oct 2020 – ~Nov 2020 · 31 days · monthly snapshot~Nov 2020 – ~Dec 2020 · 30 days · monthly snapshot~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshot~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshot~Feb 2021 – ~Mar 2021 · 28 days · monthly snapshot~Mar 2021 – ~May 2021 · 2 months · monthly snapshot~May 2021 – ~Jun 2021 · 31 days · monthly snapshot~Jun 2021 – ~Sep 2021 · 3 months · monthly snapshot~Sep 2021 – ~Oct 2021 · 30 days · monthly snapshot~Oct 2021 – ~Nov 2021 · 31 days · monthly snapshot~Nov 2021 – ~Dec 2021 · 30 days · monthly snapshot~Dec 2021 – ~Jan 2022 · 31 days · monthly snapshot~Jan 2022 – ~Feb 2022 · 31 days · monthly snapshot~Feb 2022 – ~Apr 2022 · 59 days · monthly snapshot~Apr 2022 – ~May 2022 · 30 days · monthly snapshot~May 2022 – ~Jun 2022 · 31 days · monthly snapshot~Jun 2022 – ~Jul 2022 · 30 days · monthly snapshot~Jul 2022 – ~Sep 2022 · 2 months · monthly snapshot~Sep 2022 – ~Oct 2022 · 30 days · monthly snapshot~Oct 2022 – ~Nov 2022 · 31 days · monthly snapshot~Nov 2022 – ~Dec 2022 · 30 days · monthly snapshot~Dec 2022 – ~Mar 2023 · 3 months · monthly snapshot~Mar 2023 – ~Apr 2023 · 31 days · monthly snapshot~Apr 2023 – ~May 2023 · 30 days · monthly snapshot~May 2023 – ~Aug 2023 · 3 months · monthly snapshot~Aug 2023 – ~Oct 2023 · 2 months · monthly snapshot~Oct 2023 – ~Nov 2023 · 31 days · monthly snapshot~Nov 2023 – ~Jul 2024 · 8 months · monthly snapshot~Jul 2024 – ~Aug 2024 · 31 days · monthly snapshot~Aug 2024 – ~Sep 2024 · 31 days · monthly snapshot~Sep 2024 – ~Jun 2025 · 9 months · monthly snapshot~Jun 2025 – ~Jul 2025 · 30 days · monthly snapshot~Jul 2025 – ~Sep 2025 · 2 months · monthly snapshot~Sep 2025 – present · 11 months · monthly snapshot

Change History

43 versions recorded
  1. Sep 2025 — Present [monthly]

    Active Not Recruiting PHASE3

  2. Jul 2025 — Sep 2025 [monthly]

    Active Not Recruiting PHASE3

  3. Jun 2025 — Jul 2025 [monthly]

    Active Not Recruiting PHASE3

  4. Sep 2024 — Jun 2025 [monthly]

    Active Not Recruiting PHASE3

  5. Aug 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE3

Show 38 earlier versions
  1. Jul 2024 — Aug 2024 [monthly]

    Active Not Recruiting PHASE3

  2. Nov 2023 — Jul 2024 [monthly]

    Active Not Recruiting PHASE3

  3. Oct 2023 — Nov 2023 [monthly]

    Active Not Recruiting PHASE3

  4. Aug 2023 — Oct 2023 [monthly]

    Active Not Recruiting PHASE3

  5. May 2023 — Aug 2023 [monthly]

    Active Not Recruiting PHASE3

    Status: RecruitingActive Not Recruiting

  6. Apr 2023 — May 2023 [monthly]

    Recruiting PHASE3

  7. Mar 2023 — Apr 2023 [monthly]

    Recruiting PHASE3

  8. Dec 2022 — Mar 2023 [monthly]

    Recruiting PHASE3

  9. Nov 2022 — Dec 2022 [monthly]

    Recruiting PHASE3

  10. Oct 2022 — Nov 2022 [monthly]

    Recruiting PHASE3

  11. Sep 2022 — Oct 2022 [monthly]

    Recruiting PHASE3

  12. Jul 2022 — Sep 2022 [monthly]

    Recruiting PHASE3

  13. Jun 2022 — Jul 2022 [monthly]

    Recruiting PHASE3

  14. May 2022 — Jun 2022 [monthly]

    Recruiting PHASE3

  15. Apr 2022 — May 2022 [monthly]

    Recruiting PHASE3

  16. Feb 2022 — Apr 2022 [monthly]

    Recruiting PHASE3

  17. Jan 2022 — Feb 2022 [monthly]

    Recruiting PHASE3

  18. Dec 2021 — Jan 2022 [monthly]

    Recruiting PHASE3

  19. Nov 2021 — Dec 2021 [monthly]

    Recruiting PHASE3

  20. Oct 2021 — Nov 2021 [monthly]

    Recruiting PHASE3

  21. Sep 2021 — Oct 2021 [monthly]

    Recruiting PHASE3

  22. Jun 2021 — Sep 2021 [monthly]

    Recruiting PHASE3

  23. May 2021 — Jun 2021 [monthly]

    Recruiting PHASE3

  24. Mar 2021 — May 2021 [monthly]

    Recruiting PHASE3

  25. Feb 2021 — Mar 2021 [monthly]

    Recruiting PHASE3

  26. Jan 2021 — Feb 2021 [monthly]

    Recruiting PHASE3

  27. Dec 2020 — Jan 2021 [monthly]

    Recruiting PHASE3

  28. Nov 2020 — Dec 2020 [monthly]

    Recruiting PHASE3

  29. Oct 2020 — Nov 2020 [monthly]

    Recruiting PHASE3

  30. Sep 2020 — Oct 2020 [monthly]

    Recruiting PHASE3

  31. Aug 2020 — Sep 2020 [monthly]

    Recruiting PHASE3

  32. Jul 2020 — Aug 2020 [monthly]

    Recruiting PHASE3

  33. Jun 2020 — Jul 2020 [monthly]

    Recruiting PHASE3

  34. Apr 2020 — Jun 2020 [monthly]

    Recruiting PHASE3

  35. Mar 2020 — Apr 2020 [monthly]

    Recruiting PHASE3

    Status: Not Yet RecruitingRecruiting

  36. Feb 2020 — Mar 2020 [monthly]

    Not Yet Recruiting PHASE3

  37. Dec 2019 — Feb 2020 [monthly]

    Not Yet Recruiting PHASE3

  38. Oct 2019 — Dec 2019 [monthly]

    Not Yet Recruiting PHASE3

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • AbbVie
  • Roche-Genentech
Data source: AbbVie

For direct contact, visit the study record on ClinicalTrials.gov .