deltatrials
Terminated PHASE1 INTERVENTIONAL 10-arm NCT04131556

A Study Comparing the Pharmacokinetics and Palatability of Two Candidate Pediatric Powder-for-Oral-Suspension Formulations of Maribavir to the Current Maribavir Tablet Formulation Administered in Healthy Adult Participants

A Phase 1, Open-label, Randomized, Crossover, Bioavailability, Dose Proportionality, and Food Effect Study Comparing the Pharmacokinetics and Palatability of Two Candidate Pediatric Powder-for-Oral-Suspension Formulations of Maribavir to the Current Maribavir Tablet Formulation Administered in Healthy Adult Subjects

Sponsor: Shire

Interventions Maribavir
Updated 11 times since 2019 Last updated: Aug 11, 2025 Started: Oct 25, 2019 Primary completion: Jan 6, 2020 Completion: Jan 6, 2020
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

The study was stopped because based on the planned interim analysis of the data of Part 1, palatability of both pediatric formulations was not acceptable.

A PHASE1 clinical study on Healthy Volunteers, this trial is terminated or withdrawn. The trial is conducted by Shire and has accumulated 11 data snapshots since 2019. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

~Nov 2019 – ~Dec 2019 · 30 days · monthly snapshotNot Yet Recruiting~Dec 2019 – ~Jan 2020 · 31 days · monthly snapshotRecruiting~Jan 2020 – ~Apr 2020 · 3 months · monthly snapshotRecruiting~Apr 2020 – ~Nov 2020 · 7 months · monthly snapshotTerminated~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshotTerminated~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshotTerminated~Feb 2021 – ~Dec 2021 · 10 months · monthly snapshotTerminated~Dec 2021 – ~Jul 2024 · 31 months · monthly snapshotTerminated~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotTerminated~Sep 2024 – ~Oct 2025 · 13 months · monthly snapshotTerminated~Oct 2025 – present · 9 months · monthly snapshotTerminated

Change History

11 versions recorded
  1. Oct 2025 — Present [monthly]

    Terminated PHASE1

  2. Sep 2024 — Oct 2025 [monthly]

    Terminated PHASE1

  3. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE1

  4. Dec 2021 — Jul 2024 [monthly]

    Terminated PHASE1

  5. Feb 2021 — Dec 2021 [monthly]

    Terminated PHASE1

Show 6 earlier versions
  1. Jan 2021 — Feb 2021 [monthly]

    Terminated PHASE1

  2. Nov 2020 — Jan 2021 [monthly]

    Terminated PHASE1

  3. Apr 2020 — Nov 2020 [monthly]

    Terminated PHASE1

    Status: RecruitingTerminated

  4. Jan 2020 — Apr 2020 [monthly]

    Recruiting PHASE1

  5. Dec 2019 — Jan 2020 [monthly]

    Recruiting PHASE1

    Status: Not Yet RecruitingRecruiting

  6. Nov 2019 — Dec 2019 [monthly]

    Not Yet Recruiting PHASE1

    First recorded

Oct 2019

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Shire
Data source: Takeda

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations