deltatrials
Terminated PHASE1 INTERVENTIONAL 6-arm NCT04171843

A Dose-escalation Study to Evaluate the Safety and Clinical Activity of PBCAR269A, With or Without Nirogacestat, in Study Participants With Relapsed/Refractory Multiple Myeloma

A Phase 1/2a, Open-label, Dose-escalation, Dose-expansion Study to Evaluate the Safety and Clinical Activity of PBCAR269A, With or Without Nirogacestat, in Study Participants With Relapsed/Refractory Multiple Myeloma

Sponsor: Precision BioSciences, Inc.

Updated 11 times since 2019 Last updated: Sep 18, 2023 Started: Apr 30, 2020 Primary completion: Oct 19, 2022 Completion: Oct 19, 2022
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Study was terminated due to lack of sufficient therapeutic effect

A PHASE1 clinical study on Relapsed/Refractory Multiple Myeloma, this trial is terminated or withdrawn. The trial is conducted by Precision BioSciences, Inc. and has accumulated 11 data snapshots since 2020. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

~Dec 2019 – ~May 2020 · 5 months · monthly snapshotNot Yet Recruiting~May 2020 – ~Aug 2020 · 3 months · monthly snapshotRecruiting~Aug 2020 – ~Jan 2021 · 5 months · monthly snapshotRecruiting~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshotRecruiting~Feb 2021 – ~May 2021 · 3 months · monthly snapshotRecruiting~May 2021 – ~Sep 2021 · 4 months · monthly snapshotRecruiting~Sep 2021 – ~Feb 2023 · 17 months · monthly snapshotRecruiting~Feb 2023 – ~Oct 2023 · 8 months · monthly snapshotCompleted~Oct 2023 – ~Jul 2024 · 9 months · monthly snapshotTerminated~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotTerminated~Sep 2024 – present · 22 months · monthly snapshotTerminated

Change History

11 versions recorded
  1. Sep 2024 — Present [monthly]

    Terminated PHASE1

  2. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE1

  3. Oct 2023 — Jul 2024 [monthly]

    Terminated PHASE1

    Status: CompletedTerminated · Phase: PHASE1_PHASE2PHASE1

  4. Feb 2023 — Oct 2023 [monthly]

    Completed PHASE1_PHASE2

    Status: RecruitingCompleted

  5. Sep 2021 — Feb 2023 [monthly]

    Recruiting PHASE1_PHASE2

Show 6 earlier versions
  1. May 2021 — Sep 2021 [monthly]

    Recruiting PHASE1_PHASE2

  2. Feb 2021 — May 2021 [monthly]

    Recruiting PHASE1_PHASE2

  3. Jan 2021 — Feb 2021 [monthly]

    Recruiting PHASE1_PHASE2

  4. Aug 2020 — Jan 2021 [monthly]

    Recruiting PHASE1_PHASE2

  5. May 2020 — Aug 2020 [monthly]

    Recruiting PHASE1_PHASE2

    Status: Not Yet RecruitingRecruiting

  6. Dec 2019 — May 2020 [monthly]

    Not Yet Recruiting PHASE1_PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Precision BioSciences, Inc.
Data source: Precision BioSciences, Inc.

For direct contact, visit the study record on ClinicalTrials.gov .