deltatrials
Unknown PHASE2 INTERVENTIONAL 1-arm NCT04278885

Lanadelumab in FXII-associated Cold Autoinflammatory Syndrome (FACAS) (LANA-FXII)

Factor XII-associated Cold Autoinflammatory Syndrome (FACAS) Linked to Kallikrein-kinin Pathology: Proof of Concept Treatment With Lanadelumab (DX-2930)

Sponsor: Charite University, Berlin, Germany

Interventions Lanadelumab
Updated 10 times since 2020 Last updated: Jan 4, 2024 Started: Oct 5, 2020 Primary completion: Dec 31, 2024 Completion: Dec 31, 2024
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE2 trial investigates Hereditary Autoinflammatory Disease and is currently ongoing. Charite University, Berlin, Germany leads this study, which shows 10 recorded versions since 2020 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Mar 2020 – ~Nov 2020 · 8 months · monthly snapshotNot Yet Recruiting~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshot~Jan 2021 – ~Feb 2022 · 13 months · monthly snapshotRecruiting~Feb 2022 – ~Sep 2022 · 7 months · monthly snapshotRecruiting~Sep 2022 – ~Mar 2023 · 6 months · monthly snapshot~Mar 2023 – ~Feb 2024 · 11 months · monthly snapshotRecruiting~Feb 2024 – ~Jul 2024 · 5 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Feb 2026 · 17 months · monthly snapshotActive Not Recruiting~Feb 2026 – present · 6 months · monthly snapshot

Change History

10 versions recorded
  1. Feb 2026 — Present [monthly]

    Unknown PHASE2

    Status: Active Not RecruitingUnknown

  2. Sep 2024 — Feb 2026 [monthly]

    Active Not Recruiting PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE2

  4. Feb 2024 — Jul 2024 [monthly]

    Active Not Recruiting PHASE2

    Status: RecruitingActive Not Recruiting

  5. Mar 2023 — Feb 2024 [monthly]

    Recruiting PHASE2

Show 5 earlier versions
  1. Sep 2022 — Mar 2023 [monthly]

    Recruiting PHASE2

  2. Feb 2022 — Sep 2022 [monthly]

    Recruiting PHASE2

  3. Jan 2021 — Feb 2022 [monthly]

    Recruiting PHASE2

  4. Nov 2020 — Jan 2021 [monthly]

    Recruiting PHASE2

    Status: Not Yet RecruitingRecruiting

  5. Mar 2020 — Nov 2020 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Charite University, Berlin, Germany
  • Shire International GmbH
Data source: Charite University, Berlin, Germany

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations