deltatrials
Completed PHASE3 INTERVENTIONAL 2-arm NCT04206605

A Study of Lanadelumab in Teenagers and Adults to Prevent Acute Attacks of Non-histaminergic Angioedema With Normal C1-Inhibitor (C1-INH)

A Phase 3, Multicenter, Randomized, Placebo-controlled, Double-blind Study to Evaluate the Efficacy and Safety of Lanadelumab for Prevention Against Acute Attacks of Non-histaminergic Angioedema With Normal C1-Inhibitor (C1-INH)

Sponsor: Takeda

Conditions Angioedema
Updated 14 times since 2020 Last updated: Dec 6, 2023 Started: May 4, 2020 Primary completion: Oct 20, 2022 Completion: Oct 20, 2022
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT04206605, this PHASE3 trial focuses on Angioedema and remains completed. Sponsored by Takeda, it has been updated 14 times since 2020, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Jan 2020 – ~Feb 2020 · 31 days · monthly snapshot~Feb 2020 – ~Mar 2020 · 29 days · monthly snapshot~Mar 2020 – ~May 2020 · 2 months · monthly snapshot~May 2020 – ~Jun 2020 · 31 days · monthly snapshot~Jun 2020 – ~Nov 2020 · 5 months · monthly snapshot~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshot~Jan 2021 – ~Sep 2021 · 8 months · monthly snapshot~Sep 2021 – ~Jul 2022 · 10 months · monthly snapshot~Jul 2022 – ~Nov 2022 · 4 months · monthly snapshot~Nov 2022 – ~Jan 2024 · 14 months · monthly snapshot~Jan 2024 – ~Jul 2024 · 6 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – present · 10 months · monthly snapshot

Change History

14 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE3

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE3

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE3

  4. Jan 2024 — Jul 2024 [monthly]

    Completed PHASE3

  5. Nov 2022 — Jan 2024 [monthly]

    Completed PHASE3

    Status: Active Not RecruitingCompleted

Show 9 earlier versions
  1. Jul 2022 — Nov 2022 [monthly]

    Active Not Recruiting PHASE3

    Status: RecruitingActive Not Recruiting

  2. Sep 2021 — Jul 2022 [monthly]

    Recruiting PHASE3

  3. Jan 2021 — Sep 2021 [monthly]

    Recruiting PHASE3

  4. Nov 2020 — Jan 2021 [monthly]

    Recruiting PHASE3

    Status: Active Not RecruitingRecruiting

  5. Jun 2020 — Nov 2020 [monthly]

    Active Not Recruiting PHASE3

    Status: Not Yet RecruitingActive Not Recruiting

  6. May 2020 — Jun 2020 [monthly]

    Not Yet Recruiting PHASE3

    Status: RecruitingNot Yet Recruiting

  7. Mar 2020 — May 2020 [monthly]

    Recruiting PHASE3

    Status: Not Yet RecruitingRecruiting

  8. Feb 2020 — Mar 2020 [monthly]

    Not Yet Recruiting PHASE3

  9. Jan 2020 — Feb 2020 [monthly]

    Not Yet Recruiting PHASE3

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Takeda
  • Takeda Development Center Americas, Inc.
Data source: Takeda

For direct contact, visit the study record on ClinicalTrials.gov .