deltatrials
Completed PHASE2 INTERVENTIONAL 2-arm NCT04281472

A Study to Assess the Safety and Efficacy of a Subcutaneous Formulation of Efgartigimod in Adults With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP, an Autoimmune Disorder That Affects the Peripheral Nerves) (ADHERE)

A Phase 2 Trial to Investigate the Efficacy, Safety, and Tolerability of Efgartigimod PH20 SC in Adult Patients With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

Sponsor: argenx

Conditions Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
Interventions efgartigimod PH20 SC in stage B placebo in stage B
Updated 29 times since 2020 Last updated: Jul 26, 2024 Started: Apr 15, 2020 Primary completion: May 11, 2023 Completion: May 11, 2023
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE2 clinical study on Chronic Inflammatory Demyelinating Polyneuropathy (CIDP), this trial is completed. The trial is conducted by argenx and has accumulated 29 data snapshots since 2020. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

~Mar 2020 – ~Jun 2020 · 3 months · monthly snapshot~Jun 2020 – ~Aug 2020 · 2 months · monthly snapshot~Aug 2020 – ~Sep 2020 · 31 days · monthly snapshot~Sep 2020 – ~Oct 2020 · 30 days · monthly snapshot~Oct 2020 – ~Dec 2020 · 2 months · monthly snapshot~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshot~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshot~Feb 2021 – ~Mar 2021 · 28 days · monthly snapshot~Mar 2021 – ~Apr 2021 · 31 days · monthly snapshot~Apr 2021 – ~May 2021 · 30 days · monthly snapshot~May 2021 – ~Sep 2021 · 4 months · monthly snapshot~Sep 2021 – ~Oct 2021 · 30 days · monthly snapshot~Oct 2021 – ~Dec 2021 · 2 months · monthly snapshot~Dec 2021 – ~Feb 2022 · 2 months · monthly snapshot~Feb 2022 – ~Apr 2022 · 59 days · monthly snapshot~Apr 2022 – ~May 2022 · 30 days · monthly snapshot~May 2022 – ~Jun 2022 · 31 days · monthly snapshot~Jun 2022 – ~Jul 2022 · 30 days · monthly snapshot~Jul 2022 – ~Dec 2022 · 5 months · monthly snapshot~Dec 2022 – ~Feb 2023 · 2 months · monthly snapshot~Feb 2023 – ~Apr 2023 · 59 days · monthly snapshot~Apr 2023 – ~May 2023 · 30 days · monthly snapshot~May 2023 – ~Jun 2023 · 31 days · monthly snapshot~Jun 2023 – ~Sep 2023 · 3 months · monthly snapshot~Sep 2023 – ~Jul 2024 · 10 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – ~Dec 2025 · 3 months · monthly snapshot~Dec 2025 – present · 8 months · monthly snapshot

Change History

29 versions recorded

  1. Dec 2025 — Present [monthly]

    Completed PHASE2

  2. Sep 2025 — Dec 2025 [monthly]

    Completed PHASE2

  3. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE2

  4. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE2

  5. Sep 2023 — Jul 2024 [monthly]

    Completed PHASE2

    Status: Active Not Recruiting → Completed

▶ Show 24 earlier versions

  1. Jun 2023 — Sep 2023 [monthly]

    Active Not Recruiting PHASE2

  2. May 2023 — Jun 2023 [monthly]

    Active Not Recruiting PHASE2

  3. Apr 2023 — May 2023 [monthly]

    Active Not Recruiting PHASE2

    Status: Recruiting → Active Not Recruiting

  4. Feb 2023 — Apr 2023 [monthly]

    Recruiting PHASE2

  5. Dec 2022 — Feb 2023 [monthly]

    Recruiting PHASE2

  6. Jul 2022 — Dec 2022 [monthly]

    Recruiting PHASE2

  7. Jun 2022 — Jul 2022 [monthly]

    Recruiting PHASE2

  8. May 2022 — Jun 2022 [monthly]

    Recruiting PHASE2

  9. Apr 2022 — May 2022 [monthly]

    Recruiting PHASE2

  10. Feb 2022 — Apr 2022 [monthly]

    Recruiting PHASE2

  11. Dec 2021 — Feb 2022 [monthly]

    Recruiting PHASE2

  12. Oct 2021 — Dec 2021 [monthly]

    Recruiting PHASE2

  13. Sep 2021 — Oct 2021 [monthly]

    Recruiting PHASE2

  14. May 2021 — Sep 2021 [monthly]

    Recruiting PHASE2

  15. Apr 2021 — May 2021 [monthly]

    Recruiting PHASE2

  16. Mar 2021 — Apr 2021 [monthly]

    Recruiting PHASE2

  17. Feb 2021 — Mar 2021 [monthly]

    Recruiting PHASE2

  18. Jan 2021 — Feb 2021 [monthly]

    Recruiting PHASE2

  19. Dec 2020 — Jan 2021 [monthly]

    Recruiting PHASE2

  20. Oct 2020 — Dec 2020 [monthly]

    Recruiting PHASE2

  21. Sep 2020 — Oct 2020 [monthly]

    Recruiting PHASE2

  22. Aug 2020 — Sep 2020 [monthly]

    Recruiting PHASE2

  23. Jun 2020 — Aug 2020 [monthly]

    Recruiting PHASE2

    Status: Not Yet Recruiting → Recruiting

  24. Mar 2020 — Jun 2020 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • argenx
Data source: argenx

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Aarhus, Denmark , Alicante, Spain , Amsterdam, Netherlands , Angers, France , Augusta, United States , Austin, United States , Badalona, Spain , Barcelona, Spain , Beijing, China , Belgrade, Serbia and 176 more locations