deltatrials
Terminated PHASE1/PHASE2 INTERVENTIONAL 2-arm NCT04294459

Safety, Pharmacokinetics, and Preliminary Efficacy of Isatuximab in Patients Awaiting Kidney Transplantation

A Phase 1b/2 Study to Evaluate the Safety, Pharmacokinetics, and Preliminary Efficacy of Isatuximab (SAR650984) in Patients Awaiting Kidney Transplantation

Sponsor: Sanofi

Conditions Immune System Disorder
Interventions Acetaminophen (paracetamol) or equivalent Diphenhydramine or equivalent Isatuximab SAR650984 Methylprednisolone or equivalent Montelukast or equivalent Ranitidine or equivalent
Updated 22 times since 2020 Last updated: Sep 15, 2025 Started: Jun 18, 2020 Primary completion: May 2, 2022 Completion: May 2, 2022
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Terminated due to non-safety reasons

Other terminated trials from Sanofi

See all terminations from Sanofi

A PHASE1/PHASE2 clinical study on Immune System Disorder, this trial is terminated or withdrawn. The trial is conducted by Sanofi and has accumulated 22 data snapshots since 2020. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

~Apr 2020 – ~Jun 2020 · 2 months · monthly snapshot~Jun 2020 – ~Jul 2020 · 30 days · monthly snapshot~Jul 2020 – ~Aug 2020 · 31 days · monthly snapshot~Aug 2020 – ~Sep 2020 · 31 days · monthly snapshot~Sep 2020 – ~Oct 2020 · 30 days · monthly snapshot~Oct 2020 – ~Nov 2020 · 31 days · monthly snapshot~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshot~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshot~Feb 2021 – ~Mar 2021 · 28 days · monthly snapshot~Mar 2021 – ~Apr 2021 · 31 days · monthly snapshot~Apr 2021 – ~Sep 2021 · 5 months · monthly snapshot~Sep 2021 – ~Oct 2021 · 30 days · monthly snapshot~Oct 2021 – ~Jan 2022 · 3 months · monthly snapshot~Jan 2022 – ~Feb 2022 · 31 days · monthly snapshot~Feb 2022 – ~Jun 2022 · 4 months · monthly snapshot~Jun 2022 – ~Jun 2023 · 12 months · monthly snapshot~Jun 2023 – ~Jul 2023 · 30 days · monthly snapshot~Jul 2023 – ~Jul 2024 · 12 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – ~Oct 2025 · 30 days · monthly snapshot~Oct 2025 – present · 9 months · monthly snapshot

Change History

22 versions recorded

  1. Oct 2025 — Present [monthly]

    Terminated PHASE1/PHASE2

  2. Sep 2025 — Oct 2025 [monthly]

    Terminated PHASE1/PHASE2

  3. Sep 2024 — Sep 2025 [monthly]

    Terminated PHASE1/PHASE2

  4. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE1/PHASE2

    Phase: PHASE1_PHASE2 → PHASE1/PHASE2

  5. Jul 2023 — Jul 2024 [monthly]

    Terminated PHASE1_PHASE2

▶ Show 17 earlier versions

  1. Jun 2023 — Jul 2023 [monthly]

    Terminated PHASE1_PHASE2

    Status: Completed → Terminated

  2. Jun 2022 — Jun 2023 [monthly]

    Completed PHASE1_PHASE2

    Status: Active Not Recruiting → Completed

  3. Feb 2022 — Jun 2022 [monthly]

    Active Not Recruiting PHASE1_PHASE2

    Status: Recruiting → Active Not Recruiting

  4. Jan 2022 — Feb 2022 [monthly]

    Recruiting PHASE1_PHASE2

  5. Oct 2021 — Jan 2022 [monthly]

    Recruiting PHASE1_PHASE2

  6. Sep 2021 — Oct 2021 [monthly]

    Recruiting PHASE1_PHASE2

  7. Apr 2021 — Sep 2021 [monthly]

    Recruiting PHASE1_PHASE2

  8. Mar 2021 — Apr 2021 [monthly]

    Recruiting PHASE1_PHASE2

  9. Feb 2021 — Mar 2021 [monthly]

    Recruiting PHASE1_PHASE2

  10. Jan 2021 — Feb 2021 [monthly]

    Recruiting PHASE1_PHASE2

  11. Nov 2020 — Jan 2021 [monthly]

    Recruiting PHASE1_PHASE2

  12. Oct 2020 — Nov 2020 [monthly]

    Recruiting PHASE1_PHASE2

  13. Sep 2020 — Oct 2020 [monthly]

    Recruiting PHASE1_PHASE2

  14. Aug 2020 — Sep 2020 [monthly]

    Recruiting PHASE1_PHASE2

  15. Jul 2020 — Aug 2020 [monthly]

    Recruiting PHASE1_PHASE2

  16. Jun 2020 — Jul 2020 [monthly]

    Recruiting PHASE1_PHASE2

    Status: Not Yet Recruiting → Recruiting

  17. Apr 2020 — Jun 2020 [monthly]

    Not Yet Recruiting PHASE1_PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Sanofi
Data source: Sanofi

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations