deltatrials
Completed PHASE3 INTERVENTIONAL 2-arm NCT04401579

Adaptive COVID-19 Treatment Trial 2 (ACTT-2)

A Multicenter, Adaptive, Randomized Blinded Controlled Trial of the Safety and Efficacy of Investigational Therapeutics for the Treatment of COVID-19 in Hospitalized Adults (ACTT-2)

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Conditions COVID-19
Updated 10 times since 2020 Last updated: Mar 9, 2022 Started: May 8, 2020 Primary completion: Jul 31, 2020 Completion: Jul 31, 2020
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE3 trial investigates COVID-19 and is currently completed. National Institute of Allergy and Infectious Diseases (NIAID) leads this study, which shows 10 recorded versions since 2020 — indicating substantial longitudinal coverage. Longitudinal tracking of infectious disease trials helps identify durability of treatment effects.

Status Flow

~Jun 2020 – ~Jul 2020 · 30 days · monthly snapshotRecruiting~Jul 2020 – ~Aug 2020 · 31 days · monthly snapshotRecruiting~Aug 2020 – ~Sep 2020 · 31 days · monthly snapshotActive Not Recruiting~Sep 2020 – ~Jan 2021 · 4 months · monthly snapshotActive Not Recruiting~Jan 2021 – ~May 2021 · 4 months · monthly snapshotCompleted~May 2021 – ~Apr 2022 · 11 months · monthly snapshotCompleted~Apr 2022 – ~Jul 2024 · 27 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotCompleted~Sep 2025 – present · 9 months · monthly snapshotCompleted

Change History

10 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE3

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE3

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE3

  4. Apr 2022 — Jul 2024 [monthly]

    Completed PHASE3

  5. May 2021 — Apr 2022 [monthly]

    Completed PHASE3

Show 5 earlier versions
  1. Jan 2021 — May 2021 [monthly]

    Completed PHASE3

    Status: Active Not RecruitingCompleted

  2. Sep 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE3

  3. Aug 2020 — Sep 2020 [monthly]

    Active Not Recruiting PHASE3

    Status: RecruitingActive Not Recruiting

  4. Jul 2020 — Aug 2020 [monthly]

    Recruiting PHASE3

  5. Jun 2020 — Jul 2020 [monthly]

    Recruiting PHASE3

    First recorded

May 2020

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • National Institute of Allergy and Infectious Diseases (NIAID)
Data source: National Institute of Allergy and Infectious Diseases (NIAID)

For direct contact, visit the study record on ClinicalTrials.gov .