deltatrials
Terminated PHASE1 INTERVENTIONAL 2-arm NCT04402723

Combination of Donafenib and Cytarabine/Daunorubicin in Relapsed AML

A Dose-escalated Phase Ⅰ Trial to Assess the Tolerance and Pharmacokinetics of Combination of Donafenib and Cytarabine/Daunorubicin in Relapsed AML Patient

Sponsor: Suzhou Zelgen Biopharmaceuticals Co.,Ltd

Interventions Donafenib
Updated 6 times since 2020 Last updated: Nov 28, 2022 Started: Nov 6, 2018 Primary completion: Feb 9, 2022 Completion: Feb 9, 2022
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Corporate policy adjustments

A PHASE1 clinical study on Acute Myeloid Leukemia (AML), this trial is terminated or withdrawn. The trial is conducted by Suzhou Zelgen Biopharmaceuticals Co.,Ltd and has accumulated 6 data snapshots since 2018. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Jun 2020 – ~Jan 2021 · 7 months · monthly snapshotRecruiting~Jan 2021 – ~Sep 2021 · 8 months · monthly snapshotRecruiting~Sep 2021 – ~Dec 2022 · 15 months · monthly snapshotRecruiting~Dec 2022 – ~Jul 2024 · 19 months · monthly snapshotTerminated~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – present · 23 months · monthly snapshotTerminated

Change History

6 versions recorded
  1. Sep 2024 — Present [monthly]

    Terminated PHASE1

  2. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE1

  3. Dec 2022 — Jul 2024 [monthly]

    Terminated PHASE1

    Status: RecruitingTerminated

  4. Sep 2021 — Dec 2022 [monthly]

    Recruiting PHASE1

  5. Jan 2021 — Sep 2021 [monthly]

    Recruiting PHASE1

Show 1 earlier version
  1. Jun 2020 — Jan 2021 [monthly]

    Recruiting PHASE1

    First recorded

Nov 2018

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Suzhou Zelgen Biopharmaceuticals Co.,Ltd
Data source: Suzhou Zelgen Biopharmaceuticals Co.,Ltd

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations