deltatrials
Recruiting PHASE1 INTERVENTIONAL 1-arm NCT04477343

A Study to Evaluate the Safety and Tolerability of SX-682 in Combination With Nivolumab as a Maintenance Therapy in Patients With Metastatic Pancreatic Ductal Adenocarcinoma

An Open-label Phase 1 Study to Evaluate the Safety and Tolerability of SX-682 in Combination With Nivolumab as a Maintenance Therapy in Patients With Metastatic Pancreatic Ductal Adenocarcinoma

Sponsor: Bristol-Myers Squibb

Updated 15 times since 2020 Last updated: Jun 2, 2025 Started: Nov 23, 2020 Primary completion: Jun 1, 2026 Completion: Dec 31, 2026
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT04477343, this PHASE1 trial focuses on Pancreatic Cancer and Pancreatic Ductal Adenocarcinoma and remains actively recruiting participants. Sponsored by Bristol-Myers Squibb, it has been updated 15 times since 2020, reflecting substantial change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Aug 2020 – ~Dec 2020 · 4 months · monthly snapshot~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshot~Jan 2021 – ~Jan 2022 · 12 months · monthly snapshot~Jan 2022 – ~Sep 2022 · 8 months · monthly snapshot~Sep 2022 – ~Dec 2022 · 3 months · monthly snapshot~Dec 2022 – ~Feb 2023 · 2 months · monthly snapshot~Feb 2023 – ~Sep 2023 · 7 months · monthly snapshot~Sep 2023 – ~Mar 2024 · 6 months · monthly snapshot~Mar 2024 – ~Jul 2024 · 4 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Mar 2025 · 6 months · monthly snapshot~Mar 2025 – ~Apr 2025 · 31 days · monthly snapshot~Apr 2025 – ~Jun 2025 · 2 months · monthly snapshot~Jun 2025 – ~Jul 2025 · 30 days · monthly snapshot~Jul 2025 – present · 12 months · monthly snapshot

Change History

15 versions recorded
  1. Jul 2025 — Present [monthly]

    Recruiting PHASE1

  2. Jun 2025 — Jul 2025 [monthly]

    Recruiting PHASE1

  3. Apr 2025 — Jun 2025 [monthly]

    Recruiting PHASE1

    Status: SuspendedRecruiting

  4. Mar 2025 — Apr 2025 [monthly]

    Suspended PHASE1

    Status: RecruitingSuspended

  5. Sep 2024 — Mar 2025 [monthly]

    Recruiting PHASE1

Show 10 earlier versions
  1. Jul 2024 — Sep 2024 [monthly]

    Recruiting PHASE1

  2. Mar 2024 — Jul 2024 [monthly]

    Recruiting PHASE1

  3. Sep 2023 — Mar 2024 [monthly]

    Recruiting PHASE1

  4. Feb 2023 — Sep 2023 [monthly]

    Recruiting PHASE1

  5. Dec 2022 — Feb 2023 [monthly]

    Recruiting PHASE1

  6. Sep 2022 — Dec 2022 [monthly]

    Recruiting PHASE1

  7. Jan 2022 — Sep 2022 [monthly]

    Recruiting PHASE1

  8. Jan 2021 — Jan 2022 [monthly]

    Recruiting PHASE1

  9. Dec 2020 — Jan 2021 [monthly]

    Recruiting PHASE1

    Status: Not Yet RecruitingRecruiting

  10. Aug 2020 — Dec 2020 [monthly]

    Not Yet Recruiting PHASE1

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Bristol-Myers Squibb
  • Syntrix Biosystems, Inc.
  • University of Rochester
Data source: University of Rochester

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations