A Study of JNJ-73763989 + Nucleos(t)Ide Analog in Participants Co-Infected With Hepatitis B and Hepatitis D Virus (REEF-D)
A Phase 2, Multicenter, Randomized, Double-blind, Placebo-Controlled Study With Deferred Active Treatment to Investigate the Efficacy, Safety, and Pharmacokinetics of JNJ-73763989 + Nucleos(t)Ide Analog in Participants Co-Infected With Hepatitis B and Hepatitis D Virus
Sponsor: Janssen Research & Development, LLC
This PHASE2 trial investigates Hepatitis D, Chronic and is currently completed. Janssen Research & Development, LLC leads this study, which shows 48 recorded versions since 2020 — indicating substantial longitudinal coverage. Longitudinal tracking of infectious disease trials helps identify durability of treatment effects.
Status Flow
Change History
48 versions recorded-
Sep 2025 — Present [monthly]
Completed PHASE2
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May 2025 — Sep 2025 [monthly]
Completed PHASE2
Status: Active Not Recruiting → Completed
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Apr 2025 — May 2025 [monthly]
Active Not Recruiting PHASE2
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Mar 2025 — Apr 2025 [monthly]
Active Not Recruiting PHASE2
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Feb 2025 — Mar 2025 [monthly]
Active Not Recruiting PHASE2
▶ Show 43 earlier versions
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Jan 2025 — Feb 2025 [monthly]
Active Not Recruiting PHASE2
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Dec 2024 — Jan 2025 [monthly]
Active Not Recruiting PHASE2
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Nov 2024 — Dec 2024 [monthly]
Active Not Recruiting PHASE2
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Sep 2024 — Nov 2024 [monthly]
Active Not Recruiting PHASE2
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Aug 2024 — Sep 2024 [monthly]
Active Not Recruiting PHASE2
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Jul 2024 — Aug 2024 [monthly]
Active Not Recruiting PHASE2
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Jun 2024 — Jul 2024 [monthly]
Active Not Recruiting PHASE2
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May 2024 — Jun 2024 [monthly]
Active Not Recruiting PHASE2
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Apr 2024 — May 2024 [monthly]
Active Not Recruiting PHASE2
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Mar 2024 — Apr 2024 [monthly]
Active Not Recruiting PHASE2
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Feb 2024 — Mar 2024 [monthly]
Active Not Recruiting PHASE2
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Jan 2024 — Feb 2024 [monthly]
Active Not Recruiting PHASE2
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Nov 2023 — Jan 2024 [monthly]
Active Not Recruiting PHASE2
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Oct 2023 — Nov 2023 [monthly]
Active Not Recruiting PHASE2
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Sep 2023 — Oct 2023 [monthly]
Active Not Recruiting PHASE2
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Aug 2023 — Sep 2023 [monthly]
Active Not Recruiting PHASE2
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Jul 2023 — Aug 2023 [monthly]
Active Not Recruiting PHASE2
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Jun 2023 — Jul 2023 [monthly]
Active Not Recruiting PHASE2
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May 2023 — Jun 2023 [monthly]
Active Not Recruiting PHASE2
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Apr 2023 — May 2023 [monthly]
Active Not Recruiting PHASE2
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Mar 2023 — Apr 2023 [monthly]
Active Not Recruiting PHASE2
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Feb 2023 — Mar 2023 [monthly]
Active Not Recruiting PHASE2
Status: Recruiting → Active Not Recruiting
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Dec 2022 — Feb 2023 [monthly]
Recruiting PHASE2
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Nov 2022 — Dec 2022 [monthly]
Recruiting PHASE2
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Sep 2022 — Nov 2022 [monthly]
Recruiting PHASE2
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Jul 2022 — Sep 2022 [monthly]
Recruiting PHASE2
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Jun 2022 — Jul 2022 [monthly]
Recruiting PHASE2
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May 2022 — Jun 2022 [monthly]
Recruiting PHASE2
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Apr 2022 — May 2022 [monthly]
Recruiting PHASE2
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Mar 2022 — Apr 2022 [monthly]
Recruiting PHASE2
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Feb 2022 — Mar 2022 [monthly]
Recruiting PHASE2
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Dec 2021 — Feb 2022 [monthly]
Recruiting PHASE2
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Nov 2021 — Dec 2021 [monthly]
Recruiting PHASE2
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Oct 2021 — Nov 2021 [monthly]
Recruiting PHASE2
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Sep 2021 — Oct 2021 [monthly]
Recruiting PHASE2
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Jun 2021 — Sep 2021 [monthly]
Recruiting PHASE2
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May 2021 — Jun 2021 [monthly]
Recruiting PHASE2
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Apr 2021 — May 2021 [monthly]
Recruiting PHASE2
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Mar 2021 — Apr 2021 [monthly]
Recruiting PHASE2
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Feb 2021 — Mar 2021 [monthly]
Recruiting PHASE2
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Jan 2021 — Feb 2021 [monthly]
Recruiting PHASE2
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Dec 2020 — Jan 2021 [monthly]
Recruiting PHASE2
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Oct 2020 — Dec 2020 [monthly]
Recruiting PHASE2
First recorded
Sep 2020
Trial started
Per CT.gov start date — pre-dates our first snapshot
Eligibility Summary
No eligibility information available.
Contact Information
- Janssen Research & Development, LLC
For direct contact, visit the study record on ClinicalTrials.gov .
Study Locations
Auckland, New Zealand , Barcelona, Spain , Beijing, China , Boa Vista, Brazil , Boston, United States , Bunkyō City, Japan , Camperdown, Australia , Changchun, China , Chengdu, China , Chongqing, China and 46 more locations